|Marijuana use and physical dating violence among adolescents and emerging adults: A systematic review and meta-analysis.||03/18/2017||meta-analysis, PDV, adolescent, Studies, Research, ncbi||
Findings suggest that marijuana use is associated with a 54% increase in the odds PDV (physical dating violence) victimization, and a 45% increase in the odds of perpetration. CONCLUSIONS: Findings suggest that dating violence is a correlate of marijuana use, and that association is strongest among adolescents (vs. emerging adults) and girls (vs. boys).
|Long lasting effects of chronic heavy cannabis abuse.||03/18/2017||ncbi, chronic, impaired, delusions, Long-term, Studies, Research||
The existence of hallucinations, delusions, and organic brain dysfunction in heavy cannabis users seems to be associated with cannabinoid levels in hair. The continuation of persistent symptoms 3 months after the discontinuation of cannabis abuse, was a remarkable finding. SCIENTIFIC SIGNIFICANCE: We provide evidence that chronic and heavy cannabis abuse results in long-lasting brain dysfunction in all users and in long-lasting schizophrenia-like psychotic symptoms in more than half of all users. These findings suggest a reevaluation of the current classification of cannabis as a "soft narcotic" which erroneously, therefore, is typically considered harmless. (Am J Addict 2017;XX:1-8).
|Marijuana Is Not Safe to Smoke, Researchers Say||02/14/2017||smoked, Research||
The mold and bacteria was so widespread and potentially dangerous that the UC Davis academics concluded that they cannot recommend smoking raw or dried weed. "We cannot recommend inhaling it," says George Thompson III, an associate professor of clinical medicine at the university who helped conduct the cannabis research.
|Marijuana use may be linked to temporarily weakened heart muscle||11/14/2016||heart, Studies, Research, American Heart Association||
"This development of stress cardiomyopathy in younger patients who used marijuana suggests a possible link that needs to be further investigated," said Sahil Agrawal, M.D., co-author of the paper and also a chief cardiology fellow at St. Luke's.
Marijuana users were more likely than non-users to have a history of depression (32.9 percent vs. 14.5 percent), psychosis (11.9 percent vs. 3.8 percent), anxiety disorder (28.4 percent vs. 16.2 percent), alcoholism (13.3 percent vs. 2.8 percent), tobacco use (73.3 percent vs. 28.6 percent) and multiple substance abuse (11.4 percent vs. 0.3 percent). Because some of these can increase the risk of stress cardiomyopathy, the researchers adjusted for known risk factors to investigate the association between marijuana use and stress cardiomyopathy.
|Complexities in understanding and addressing the serious public health issues related to the nonmedical use of prescription drugs||09/01/2016||Studies, Research, Prescription, epidemic, 2017 Legislative||
A common theme among every article in this issue is the overlap be- tween NMUPD, excessive drinking, and marijuana and other forms of substance use. In every investigation, nonmedical users were observed to have a history of using alcohol, marijuana, tobacco, and other psycho- active substances. Kalyanam, Katsuki, Lanckriet, and Mackey (2017)
|What Scientific & Medical Journals & Experts Say About Marijuana||08/31/2016||Arizona, Research||
30 Referenced Resources
|Marijuana Use: Detrimental to Youth||04/01/2016||American Academy of Pediatrics, youth, Research, Side-Effects||
In summary, marijuana use is harmful to children and adolescents. For this reason, the American College of Pediatricians opposes its legalization for recreational use and urges extreme caution in legalizing it for medicinal use. Likewise, the American Academy of Child and Adolescent Psychiatry (AACAP) recently offered their own policy statement opposing efforts to legalize marijuana. They similarly pointed out that “marijuana’s deleterious effects on adolescent brain development, cognition, and social functioning may have immediate and long-term implications, including increased risk of motor vehicle accidents, sexual victimization, academic failure, lasting decline in intelligence measures, psychopathology, addiction, and psychosocial and occupational impairment.” Thus the AACAP (a) opposes efforts to legalize marijuana, (b) supports initiatives to increase awareness of marijuana’s harmful effects on adolescents, (c) supports improved access to evidence-based treatment, rather than emphasis on criminal charges, for adolescents with cannabis use disorder, and (d) supports careful monitoring of the effects of marijuana-related policy changes on child and adolescent mental health.49 The College agrees with this position on marijuana.
|Adolescent Cannabinoid Exposure Induces a Persistent Sub-Cortical Hyper-Dopaminergic State and Associated Molecular Adaptations in the Prefrontal Cortex||01/04/2016||Brain, adolescent, Research||
Thus, adolescent THC exposure induced behavioral abnormalities resembling positive and negative schizophrenia-related endophenotypes and a state of neuronal hyperactivity in the mesocorticolimbic dopamine (DA) pathway. Furthermore, we observed profound alterations in several prefrontal cortical molecular pathways consistent with sub-cortical DAergic dysregulation. Our findings demonstrate a profound dissociation in relative risk profiles for adolescent versus adulthood exposure to THC in terms of neuronal, behavioral, and molecular markers resembling neuropsychiatric pathology.
|Pot Science: Top Marijuana Findings of 2015||12/29/2015||Research, usage, college, Resource Paper, edibles, Teens||
Although studies are beginning to show that some ingredients in marijuana are likely to be helpful for people with certain conditions, the findings have yet to nail down the specifics about the dose, the frequency, the best form to take (such as getting the active compounds from edible products or smoking it), the risks from frequent use, and whether marijuana works as well as or better than other available treatments, Budney said.
|Medical Associations Response||10/11/2015||response, medical association, Research||
The American Medical Association (AMA) has opposed legalizing marijuana for medical use for many years due to the lack of evidence to support such action. In addition to AMA, the following medical associations also oppose legalizing marijuana or any of its components for medical use before FDA-quality evidence is available.
|Cannabis, cannabinoids and cancer – the evidence so far||10/11/2015||cancer, hash oil, Research||
At the moment, there simply isn’t enough evidence to prove that cannabinoids – whether natural or synthetic – works to treat cancer in patients, although research is ongoing. And there’s certainly no evidence that ‘street’ cannabis can treat cancer.
|Public Policy Statement on Marijuana, Cannabinoids and Legalization||09/21/2015||Research, legalization, asam, Long-term, Pregnancy, adolescent, youth, cigarettes||
Given these statistics.... is legalization worth the consequences....
|ASAM Public Policy Statement on Marijuana, Cannabinoids and Legalization||09/21/2015||Pregnancy, addiction, cigarettes, edibles, Research, Studies||
|Why researching cannabis is difficult||09/09/2015||Research, cancer||
There are difficulties in researching the effects of cannabis.
|Medicinal and Recreational Marijuana: What are the Risks?||07/31/2015||Teens, Research, Studies, Brain, addiction, anxiety, depression, Resource Paper||
Brain abnormalities and memory problems were observed in these individuals in their early twenties, two years after they had stopped using marijuana. The cannabis users were noted to have striatal, globus pallidus, and thalamus changes showing these brain regions appearing to shrink and collapse inward. These individuals also had poorer working memory. The earlier the age of cannabis use, the more dramatic the brain changes and memory deficits were noted to be.
|The Relationship Between Marijuana Use and Intimate Partner Violence in a Nationally Representative, Longitudinal Sample||07/14/2015||adolescent, crime, Domestic Violence, Research, USF, UF||
Adolescent marijuana use, particularly consistent use throughout adolescence, is associated with perpetration or both perpetration of and victimization by intimate partner violence in early adulthood. These findings have implications for intimate partner violence prevention efforts, as marijuana use should be considered as a target of early intimate partner violence intervention and treatment programming.
|How Cannabis Causes Paranoia: Using the Intravenous Administration of Δ9-Tetrahydrocannabinol (THC) to Identify Key Cognitive Mechanisms Leading to Paranoia||07/10/2015||Schizophrenia, paranoia, Studies, Research||
The principal psychoactive constituent of cannabis is Δ9-tetrahydrocannabinol (THC). THC administered intravenously is characterized by the appearance of psychopharmocological effects within 5 minutes, which continue for at least 90 minutes, providing an excellent experimental window. In within-subjects tests with nonclinical volunteers, D'Souza, in particular, has shown that intravenous administration of THC causes schizophrenia-like symptoms, perceptual disturbances, anxiety, and impaired working memory (eg, Morrison et al and D'Souza et al[14,15]). Similar but more pronounced results were found in patients with schizophrenia.
|Medical marijuana and children don't mix, most Americans say.||07/08/2015||Research, Children||
However, there is little science about the safety or efficacy of treating children with medical marijuana. Research also indicates that the brains and nervous systems of children and adolescents are especially vulnerable to adverse effects of marijuana use, a concern raised by the American Academy of Pediatrics and American Academy of Child and Adolescent Psychiatry. Poll
|ACOG: Doctors Should Urge Against Prenatal Marijuana Use||06/25/2015||Pregnancy, Doctors, Research||
Studies show that children exposed to marijuana in utero have lower scores on tests of visual problem-solving, visual and motor coordination, and visual analysis, compared with children not exposed to the drug, the report states. Prenatal marijuana exposure also has been associated with decreased attention span and behavioral problems. The nervous system of a human fetus can respond to the chemicals in marijuana within 14 weeks of gestation, and studies have shown that 14-year-olds are more likely to be marijuana users if their mothers used the drug during pregnancy.
|Cannabinoids for Medical Use A Systematic Review and Meta-analysis||06/20/2015||meta-analysis, Research, 2017 Legislative||
A systematic review of the benefits and adverse events (AEs)
|Marijuana Use and PTSD among Veterans||06/05/2015||Veterans, PTSD, mental health, Studies, Research||
Marijuana use for medical conditions is an issue of growing concern. Some Veterans use marijuana to relieve symptoms of PTSD and several states specifically approve the use of medical marijuana for PTSD. However, controlled studies have not been conducted to evaluate the safety or effectiveness of medical marijuana for PTSD. Thus, there is no evidence at this time that marijuana is an effective treatment for PTSD. In fact, research suggests that marijuana can be harmful to individuals with PTSD.
|Clearing the Haze||06/05/2015||Research, regulation, crime, addiction, Colorado||
The Gazette kicks off a four-day perspective series, "Clearing the Haze," that examines health, social, regulatory and financial issues associated with the world's boldest experiment with legal marijuana.
|Research Shows That Any Dose of Alcohol Combined With Cannabis Significantly Increases Levels of THC in the Blood||05/25/2015||alcohol, Research, vehicle||
Experts agree, however, that the combination of cannabis and alcohol raises the chance of crashing more than either substance by itself. In a study of 1,882 motor vehicle deaths, the U.S. Department of Transportation found an increased accident risk of 0.7 for cannabis use, 7.4 for alcohol use, and 8.4 for cannabis and alcohol use combined.
|Smoking marijuana may cause early puberty and stunts growth in boys||05/20/2015||youth, Studies, Research, puberty||
Boys who smoke marijuana go through puberty earlier but grow more slowly than those who have never smoked the drug according to a study presented today at the European Congress of Endocrinology in Dublin, Ireland. The findings will lead to a better understanding of the dangers of drug abuse on growth and development of children.
|Marijuana users may have ‘false memories’||04/22/2015||Brain, Biomedical, youth, memory, Studies, Research||
Participants in a study who had used the drug daily for around three years in their teens had an abnormally shaped hippocampus by the time they were in their early 20s.
|Letter from American Epilpsey Society||03/22/2015||Charlotte's Web, epilepsy, Legislation, Colorado, Studies, Research||
A study by a team from Children's Hospital Colorado that was presented during the AES Annual Meeting in December 2014 and has recently been accepted for publication in the journal Epilepsy & Behavior, found that artisanal "high CBD" oils resulted in no significant reduction in seizures in the majority of patients and in those for whom the parents reported improvements, these improvements were not associated with improvement in electroencephalograms (EEGs), the gold standard monitoring test for people with epilepsy.
Additionally, in 20% of cases reviewed seizures worsened with use of cannabis and in some patients there were significant adverse events. These are not the stories that you have likely
heard in your public hearings, but they are the reality of practitioners at Children's Hospital Colorado who have cared for the largest number of cases of children with epilepsy treated with cannabis in the U.S.
|The Impact of Marijuana Policies on Youth: Clinical, Research, and Legal Update||03/01/2015||youth, American Academy of Pediatrics, AAP, Studies, Research||
· These consequences include impaired short-term memory and decreased concentration, attention span, and problem solving, which clearly interfere with learning. Alterations in motor control, coordination, judgment, reaction time, and tracking ability have also been documented; these may contribute to unintentional deaths and injuries among adolescents (especially those associated with motor vehicles if adolescents drive while intoxicated by marijuana).
|Researchers warn of “significant link” between marijuana and mania||02/16/2015||Research, England, adolescent, mania, Studies||
New research out of Britain’s has found a “significant link” between marijuana use and mania, which can range from hyperactivity and difficulty sleeping to aggression, becoming delusional and hearing voices
|Marijuana and Opioid "Cross Talk" Risks for the Born, the Unborn||02/09/2015||madras, Research, powerpoint, opioid|
|Medical Marijuana: The State of the Science||02/06/2015||Studies, Research, medscape, mental health, Side-Effects, heart, lungs, body, Brain, youth, cannabis, Resource Paper||
Medical cannabinoids are here to stay, but intellectual honesty is imperative if we are moving toward exploiting their potential benefits. Owing to rising THC concentrations of products, "medical" marijuana is rarely good medicine. This review has identified the dangers associated with wholeplant marijuana, whether used for recreational or for supposedly medical purposes.
|The Impact of Marijuana Policies on Youth: Clinical, Research, and Legal Update||01/26/2015||youth, clinical, Research, legalization, pedestrians|
|Medical Marijuana May Worsen PTSD Symptoms, Increase Violence. Medscape. Dec 15, 2014.||12/16/2014||Research, PTSD, Veterans, Studies|
|Long-term effects of marijuana use on the brain||10/13/2014||Long-term, Side-Effects, Brain, Research, Studies|
|What has research over the past two decades revealed about the adverse health effects of recreational cannabis use?||10/07/2014||Studies, Research, recreational|
|Medical marijuana laws in 50 states: investigating the relationship between state legalization of medical marijuana and marijuana use, abuse and dependence.||08/01/2014||Research|
|Birth outcomes associated with cannabis use before and during pregnancy.||08/01/2014||Pregnancy, Research|
|Pot Legalization vs. Science||07/30/2014||legalization, Research|
|Comparing Alcohol and Marijuana: Seriously||07/27/2014||alcohol, Research, youth|
|Medical Marijuana as a new herbalism (Part 1)||07/07/2014||Gorbski, Studies, Research|
|The Marijuana Report||07/07/2014||Research, national, Studies, article|
|Two 24-Week Phase 3 Studies of Lumacaftor in Combination with Ivacaftor Met Primary Endpoint with Statistically Significant Improvements in Lung Function||06/24/2014||Cystic Fibrosis, FDA, Research|
|NIDA review summarizes research on marijuana’s negative health effects||06/19/2014||Research, Studies, addiction, second hand smoke, chemicals||
The reviewers consider areas in which little research has been conducted. This includes possible health consequences of secondhand marijuana smoke; the long-term impact of prenatal marijuana exposure; the therapeutic potential of the individual chemicals found in the marijuana plant; and effects of marijuana legalization policies on public health.
|Medical marijuana laws in 50 states: investigating the relationship between state legalization of medical marijuana and marijuana use, abuse and dependence||06/13/2014||legalization, youth, Studies, Research||
States that legalized medical marijuana had higher rates of marijuana use. Future research needs to examine whether the association is causal, or is due to an underlying common cause, such as community norms supportive of the legalization of medical marijuana and of marijuana use.
|Man's fertility, Research finds....||06/05/2014||health, men, Research|
|NIDA review summarizes research on marijuana’s negative health effects||06/05/2014||health, car crashes, Impairment, Research||
The authors review literature showing that marijuana impairs driving, increasing the risk of being involved in a car accident and that these risks are further enhanced when combining marijuana with alcohol.
|Casual marijuana use linked with brain abnormalities, study finds||04/15/2014||Research, Brain, young adults, Studies||
For the first time, researchers at Northwestern University have analyzed the relationship between casual use of marijuana and brain changes – and found that young adults who used cannabis just once or twice a week showed significant abnormalities in two important brain structures.
|Heavy, Frequent Cannabis Use Linked to Mental Illness||04/03/2014||Research, addiction, mental health, usage||
A new study suggests people with mental illness are more than seven times as likely to use marijuana weekly than people without a mental illness.
In total, 4.4 percent of individuals with a mental illness in the past 12 months reported using cannabis weekly, compared to 0.6 percent among individuals without any mental illness.
Cannabis use disorders occurred among 4 percent of those with mental illness versus 0.4 per cent among those without.
Researchers also noted that, although cannabis use is generally higher among younger people, the association between mental illness and cannabis use was pervasive across most age groups.
|Cannabis During Pregnancy Impairs Baby's Brain Development||01/28/2014||Pregnancy, Research|
|Epilepsy experts call for more research into medical marijuana||01/22/2014||epilepsy, Research|
|Marijuana and Drugged Driving||06/11/2013||car crashes, impaired, IBH, Research, Studies, car crashes||
Institute for Behavioral and Health-
|Psychomotor Function in Chronic Daily Cannabis Smokers during Sustained Abstinence||01/02/2013||Studies, Research, chronic||
Conclusions/Significance: Sustained cannabis abstinence moderately improved critical tracking and divided attention performance in chronic, daily cannabis smokers, but impairment was still observable compared to controls after 3 weeks of
abstinence. Between group differences, however, need to be interpreted with caution as chronic smokers and controls were not matched for education, social economic status, life style and race.
|Acute cannabis consumption and motor vehicle collision risk: systematic review of observational studies and meta-analysis||12/11/2012||Studies, Research, car crashes, meta-analysis, Fatalities||
Acute cannabis consumption is associated with an increased risk of a motor vehicle crash, especially for fatal collisions. This information could be used as the basis for campaigns against drug impaired driving, developing regional or national policies to control acute drug use while driving, and raising public awareness.
|Effects of Marijuana on the Fetus and Breastfeeding Infants.||09/18/2012||Pregnancy, Research|
|If You Thought Marijuana was Harmless, Medical Researchers Have News for You||04/01/2012||health, addiction, pills, youth, Research, social costs||
As expected, prescription cannabinoids are effective antiemetics and appetite stimulants, and some studies report their effectiveness as adjunct therapy in chronic pain syndromes, spasticity, and glaucoma. Similar results are reported by the few studies of smoked cannabis plant for these same indications. As noted earlier, safe and effective alternative treatments for all these syndromes are available. Studies assessing psychological aspects of smoked cannabis and prescription cannabinoids uniformly report undesired effects: acute psychosis, poorer prognosis of chronic psychosis, or cognitive dulling in medical patients.
|Legalization, Decriminalization & Medicinal Use of Cannabis:A Scientific and Public Health Perspective||03/01/2012||Research, Studies, Psychosis, Glaucoma, mental health, organs, risks|