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Researchers have raised particular concern about synthesized products that isolate chemicals like 7-hydroxymitragynine, saying they could carry risks that are different from the kratom leaf long used in Thailand or Malaysia. McCurdy said when that chemical is isolated, "it's no longer really a kratom product."

kratom
madras

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2024 Amendment 3

Matthew Lowe, executive director of the advocacy group Global Kratom Coalition, said some synthetic products have "very, very high doses" of a particular chemical found in scant amounts in kratom leaf material. Several kratom researchers have warned that chemical — 7-hydroxymitragynine — poses a higher risk of abuse.
"It certainly isn't kratom as nature intended," said Lowe, whose organization supports the California bill. Kratom products should have "the same ratios as the alkaloids are found within nature."

kratom

DELTA-8 THC

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Delta-8
legalization

Yeah, so apparently rats have infested the evidence room down there at HQ and are feasting on the drugs that have been confiscated by police.
I mean, maybe they’re easier to trap when they’re high?
The NOPD is asking city council for funding the move into a new building, because apparently working with a bunch of stoner vermin isn’t exactly ideal conditions?
But hey, it’s still not as bad as some of the people you see on Bourbon Street after a night of partying…

rats, fatal

Smoking marijuana impacts blood flow in the brain and body, decreases respiration and body temperature, contributes to airway blockages, raises blood pressure, increases heart rate, impacts heart rhythm, and more — all of which can make recovery from surgery more difficult, according to a November 2019 review of literature. Use of marijuana also increases post-op pain, according to an October 2020 study.

 
The new study’s finding is significant, the authors said, considering prior analyses have found nearly 3 of every 10 marijuana users develop a dependence on weed called cannabis use disorder.

1. Today's marijuana is not just a plant - it is genetically modified, potent and contains toxins

2. Marijuana can have contaminants and toxins.

3. The drug industry targets youth

4. Marijuana stunts brain growth 

5. Marijuana is Addictive

6. Marijuana is a risk factor for psychosis and schizophrenia....
 

Delta-8, Side-Effects, addiction
seizure
Delta-8

We were told those seven students had to be rushed to the hospital after ingesting the gummies that officials said were brought to school by a student.
The sirens of first responders were heard loud and clear outside of the school Tuesday afternoon.
The seven students were taken to Texas Children’s and Kingwood hospitals after ingesting the gummies.
It’s unclear who originally gave one of the students those gummies, but if you’re 21 and up and live in Texas you can buy multiple forms of THC in most gas stations.

Delta-8
Delta-8, poisoning

Summary: Significant psychiatric risks associated with high-THC cannabis concentrates, demonstrating that even in healthy adults, THC can induce a range of psychiatric symptoms, including psychosis. Given these findings, there's a strong argument for legislative action to limit THC potency in marijuana products to a maximum of 15% to safeguard public health. This precautionary measure is particularly crucial as the legal status of cannabis may lead individuals to perceive it as safe. Legislators have a responsibility to protect the public by implementing regulations that address the potency of cannabis products, prioritizing the well-being of those who may not be aware of the risks associated with high-THC consumption.

Potency, Psychosis

Between May 1, 2010, and April 1, 2015, we obtained data from 901 patients with first-episode psychosis across 11 sites and 1237 population controls from those same sites. Daily cannabis use was associated with increased odds of psychotic disorder compared with never users, increasing to nearly five-times increased odds for daily use of high-potency types of cannabis" "Use of high-potency cannabis (THC ≥10%) Use of high-potency cannabis was a strong predictor of psychotic disorder in Amsterdam, London, and Paris where high-potency cannabis was widely available"

Potency

THC exposure during adolescence may cause microglial cell death and brain changes, increasing schizophrenia risks in genetically susceptible individuals.
 
Earlier, a 2023 study found heavy marijuana use may trigger schizophrenia, particularly in young men. This study examined the health records of nearly 7 million Danish citizens and determined that up to 30% of schizophrenia diagnoses — around 3,000 in total — could have been prevented if young men hadn’t abused marijuana.

THC, Brain, Delta-8, Research

Excellent history and scientific information. 

suicide

Marijuana and hemp are made up of hundreds of cannabinoids, including Delta-9 THC, the psychoactive component of marijuana that makes people feel “high” and CBD. Delta-8 THC is a cannabinoid found in the hemp plant and is structurally similar to Delta-9 THC. Because Delta-8 THC is virtually identical to Delta-9 THC, it carries similar risks including risks of addiction and psychosis. In the 2018 Farm Bill, Congress legalized hemp and any hemp-derived products, including Delta-8 THC. As a result, Delta-8 products have popped up in virtually every state and are available at convenience stores and gas stations. 

 

Hemp Loophole, Laws

Millions of Americans believe marijuana relieves pain, reduces anxiety, improves your mood, and has no side effects. Are they right? Dr. Drew Pinsky, physician, addiction medicine specialist, and media personality, answers this question.

prager u, legalization

To enforce the changes, FDACS conducted “the largest ever inspection sweep of businesses selling products that contain hemp extracts in July and August,” a Department press note said. That included examinations of more than 700 businesses across all 67 Florida counties and resulted in the discovery of 83,000 packages of hemp-extract products that wouldn’t look out of place in a candy aisle.

Delta-8, Delta-8 FL

Cannabis legalization efforts are a boon to big business, but many Americans are paying with their health.

 

The hazy narrative of harmless recreation masks darker truths now coming to light. Evidence is mounting that the push for recreational drug use has led to increases in cannabis-related hospitalizations and links to mental health issues such as anxiety, depression, cannabis use disorder, and more.

Public Health, legalization, epoch times

A 12-year-old girl was sent to the hospital after she ate what she told FOX 13 she thought was a piece of candy given to her by another student. The seventh grader, Amanda, said at one point, she thought she was going to die. Her parents said she suffered a severe allergic reaction and couldn't breathe. 

 

Delta-8, Delta-8 Children

Researchers detail how lawmakers and regulators could establish key guardrails for selling and using the herb.

 

The kratom association says it has reported dozens of kratom companies to the FDA for making medical claims. When asked for these reports, the association declined to share them.
Haddow, the association lobbyist, recently told CBS News that the industry has about 8,000 players. When asked how many are legitimate, he responded: “I would say three dozen, maybe a few more than that.”

Haddow- is a highly paid national lobbyist for the Kratom industry.  

 

kratom

kratom

Excellent, comprehensive research on Kratom.  Printalbe format. 

kratom

Both hemp and marijuana plants are the same species. The main difference lies in how much of a certain cannabinoid each contains.  It’s a common misconception that hemp and marijuana are two different species of plant.  In fact, they’re not distinct speciesTrusted Source at all. They’re just two different names for cannabis, a type of flowering plant in the Cannabaceae family.
 

Delta-8, hemp

Surge of THC products, vapes has states struggling to regulate the booming market

Delta-8, Delta-8 Children

The Times requested Florida autopsy reports citing kratom or one of its major chemical compounds, an alkaloid called mitragynine, as a cause of death or contributing factor dating back to 2010.
No news organization has ever done this on a large scale. The requests initially turned up more than 600 cases. Reporters handbuilt a database to track the overdoses and key details about them, including blood-mitragynine concentrations, contributing medical conditions and every substance flagged in a person’s system during toxicology testing.
A Times investigation found more than 580 fatal kratom-related overdoses in Florida.

kratom

Some of the tactics in the kratom business may sound familiar. They mirror the strategies that were used for another controversial product — synthetic cannabis compounds, or “Spice.”

 

More than a decade ago, U.S. officials spotted a trend. Importers, court records show, were slipping Spice into the country from China by calling the white chemicals “cosmetics” or “sodium.” Products found at gas stations promised Spice was “herbal incense” or “not for human consumption.”

kratom

As medical examiners log an increasing number of overdoses involving kratom across Florida and elsewhere, the industry has largely operated without government constraints or safety measures that could help protect consumers.
Florida lawmakers considered banning kratom three times in the past decade. But industry advocates successfully fought the efforts, ensuring powders, gummies and liquid extracts are readily available at gas stations and smoke shops from Pensacola to Miami. The products vary dramatically in strength — but manufacturers don’t have to disclose or limit their intensity at all.

kratom

The development of the unregulated market for THCA cannabis. THCA is a naturally occurring cannabinoid that converts to THC when heated. It is legal in all 50 states. So, even Texas and Florida you can walk into a smoke shop and legally purchase cannabis—that in many cases is high quality—at reasonable prices. It's a brilliant example of the unstoppable energy and ingenuity of the community. We will get cannabis to the people no matter what obstacle is put in our way.

Marketplace, Delta-8

"The lack of federal regulatory clarity surrounding consumer products containing delta-8 THC and other potentially intoxicating hemp-derived cannabinoids frustrates state legislators' efforts to protect their consumers and public health," said Florida Senator Colleen Burton, a member of NFWL who supported the resolution.

Delta-8

The Times bought the products from online vendors, gas stations, smoke shops and other businesses around the region. Below are the key testing results for each product.
They are ordered most potent to least, by product type, based on mitragynine levels. The Times also tested one product containing a large amount of 7-hydroxymitragynine, another kratom alkaloid that is more potent than mitragynine.
READ ARTICLE FOR SUMMARY OF EACH PRODUCT.
Sample of product summary

  • The package the product was sent in came with a printed-out sheet showing testing results for mitragynine, 7-hydroxymitragynine, heavy metals and bacteria. A section of the report showing who ordered the results was blacked out.
  • The product’s label advertised “pain relief + mood enhancement.” Federal law prohibits kratom companies from making medical claims on packaging or in advertising because the substance is not an approved drug.
  • This product had nine times as much mitragynine as Sharma believes is safe to consume over an entire day.
  • This product type was found at the scenes of two kratom-only overdoses in Florida.
  • This product type was found at the scene of a kratom-only overdose in Florida.
  • This product type was found at the scenes of two kratom-only overdoses in Florida.
kratom

He decided to try kratom, a dusty green psychoactive powder from the leaves of a Southeast Asian tree. It was marketed as a safe way to ease anxiety and mimic the effects of opioids. It was legal, virtually unregulated and described as all-natural. He could find it at gas stations, cafes, smoke shops or online.
He took it regularly, including before paramedics were called to his home in April 2021.

kratom

Spejcher told police who responded at the time that she had smoked marijuana before the alleged incident, the VC Star reported. That marijuana was so strong that it caused her to feel like she had died and had to fight her way out of it. 

cannabis-induced psychosis

Abstract Cannabis is the most commonly abused drug in the world. In Egypt, the Anti Narcotic General Administration showed that the narcotics problem costs the Egyptian economy approximately 800 million dollars annually. LD50, lethal dose that kills 50% of the treated animals, of the bango was determined and then selected groups of rats were given tenth of LD50 for 90 days.
All over the world, there is growing interest in the part played by drugs in traffic accidents, and how to investigate adequate measures to reduce their incidence.2 Africa is the second largest producer of herbal cannabis in the world.3 In Egypt, drug addiction is considered one of the serious problems that worry both people and government. It affects young people within their productive years. It may lead to many problems such as social maladaptation, decreased works productivity and job loss.4 ‘Bango’ is the name of cannabis leaves used in Egypt and North Africa.5
Conclusion In conclusion, the present study revealed the bad effects of the bango plant on different organs in animals. Bango abuse leads to severe effects on different organs and this may subsequently lead to apoptosis and fibrosis of the organs, and this depends mainly on the dose and duration of administration.

study, Research, rats

Judge backs increased license fee for medical marijuana companies in Florida

Dept. of Health

To report concerns about a retailer who sells snacks containing hemp-derived products, contact:

Delta-8 FL, Delta-8, Delta-8 Children

Meghan Martin is a pediatric emergency room physician, a mom of four, and now, a TikTok star, with 1.3 million followers and several videos getting picked up everywhere from Good Morning America to Scary Mommy.

Delta-8, Delta-8 Children
Medical marijuana, Medical

HUNTINGTON, W.Va. (WSAZ) - A mother is facing child neglect charges after her 3-year-old was rushed to the hospital after possibly eating THC gummies, according to West Virginia State Police.
The incident on Monday, Nov. 20, in Mingo County is detailed in a criminal complaint that states Billie Sue Vandyke fell asleep for about two hours at a home along Alex Lane in Justice, West Virginia.
When she woke up, the criminal complaint states Vandyke found her 3-year-old lying on the bed and she could not wake him up.

Delta-8, Delta-8 Children

Marijuana and the Risks to Pregnancy & Breastfeeding

Marijuana contains almost 500 components including the psychoactive ingredient THC that can pass through the placenta to the baby during pregnancy, causing harm to the fetus.
Marijuana use by a breastfeeding mother can expose the newborn to toxins stored in the mother’s fat tissues and slowly released to baby, even after the mother has stopped using.
Learn about the various risks of using marijuana during pregnancy and while breastfeeding through the resources below.

 

Pregnancy, Breastfeeding

What are the potential health effects of using marijuana during my pregnancy?
Marijuana use during pregnancy can be harmful to your baby’s health.1 The chemicals in marijuana (in particular, tetrahydrocannabinol or THC) pass through your system to your baby and may harm your baby’s development.2
 

Pregnancy
Delta-8 Children

Panel begins at 17 minutes; Public Comment at 1:33:00

Delta-8, Delta-8 FL
Pregnancy, car crashes, Children, pediatrics, Delta-8, Delta-8 Children

When teenagers smoked marijuana back in 1995, the amount of THC, or active ingredient in the drug, was about 4%. But times have changed. With new methods of testing, growing, and regulating marijuana, teens now have access to cannabis with increasingly higher levels of THC. One study found that in 2017 the average potency of marijuana had increased to 17%. This increased potency, plus easier access to many forms of marijuana in recent years, has some dedicated healthcare professionals working to address the possible mental health effects marijuana use may be having on young users, including the risk for psychosis.

cannabis-induced psychosis, Delta-8, Research

An emergency room pediatrician is seeing an uptick in children consuming pot-laced edibles that often look and taste like regular candy — and these kids get more than a sugar high.
“Some kids come in and they’re really drowsy, and some are unresponsive," Dr. Meghan Martin tells TODAY.com. "Both scenarios are terrifying for the families, and it's becoming more and more common."

Delta-8 Children, Delta-8

Ellen Snelling is with the Hillsborough County Anti-Drug Alliance. She said that state lawmakers should have outright banned the sale of Delta-8 as part of the hemp bill passed earlier this year.
“This law is a great step in the right direction but, in my opinion, not nearly enough,” Snelling told the committee. “I supported the original bill that did set limits and caps on THC content. THC limits are needed — and even better, in my opinion, to have a complete ban on these hemp-synthesized intoxicants to protect public health and safety.”

Delta-8
Delta-8

“These products have not been deemed safe by any Nebraska or regulatory body,” he said. “In fact, even states where marijuana is legalized outlaw synthetically produced THCs, including delta-8, or place significant limits on their use.”
Consuming as little as 2.5 milligrams of a THC-containing gummy can “exceed the toxicity threshold” for a 3-year-old child and send that child to the hospital, the lawsuits say.

Delta-8

 In conclusion, emerging data on the correlation between cannabis use and suicide risk in patients with schizophrenia or other schizophrenic spectrum disorders are insufficient to draw firm conclusions. Nonetheless these studies seem to suggest a positive correlation of cannabis use with increased suicide risk, particularly regarding first episode psychosis (FEP) and male gender. Clinicians should be aware of the possibility of a higher risk of suicidal behavior associated specifically with cannabis use for men and patients during FEP.

suicide, cannabis-induced psychosis
Delta-8 Children, Delta-8

EXCELLANT ARTICLE

Cannabinoid Hyperemesis Syndrome  
I've seen cannabinoid hyperemesis syndrome several times in the past few years. It occurs in daily to weekly pot users. Very rarely, it can cause cerebral edema, but it is also associated with seizures and dehydration that can lead to hypovolemic shock and kidney failure.

Delta-8, health, Hyperemesis Syndrome

Conclusions: Our study provides evidence for the association between cannabis use disorder (CUD) and suicide risk among hospitalized adolescents and underscores the importance of recognizing and addressing co-occurring mental and substance use disorders along with CUD to mitigate suicide risk. Identifying high-risk adolescents in inpatient settings provides an opportunity for intervention.

Delta-8, Cannabis-use disorder, suicide

"To see his whole body shaking, not being able to open his eyes, is something I would never forget," Claudia Curiel said

hospitalization, edibles, Delta-8, Delta-8 Children

A total of eight children ranging from 6 to 8 years of age consumed the gummies. Six of the children were transported to Broward Health and Florida Medical Center, according to Lauderhill Fire Rescue officials.
CALLS TO POISON CENTERS FOR ADHD MEDICATION ERRORS HAVE RISEN 300% SINCE 2000, STUDY FINDS

Delta-8 FL, Delta-8, Delta-8 Children

Delta-8 THC Legal Status by State 10/11/2023

Delta-8

HARRISONBURG, Va. (WHSV) - According to the CDC in 2022, 36% of 12th graders reported using marijuana sometime in 2022. 6% reported daily use at least within 30 days of the survey and study being sent out.
In the commonwealth of Virginia, it is illegal to consume and purchase cannabis under the age of 21. However, Blue Ridge Poison Center reports their largest demographic of people suffering from cannabis related issues are children under the age of 21.

hospitalization, Children
Pregnancy

Tianeptine is banned in several other states including Alabama, Georgia, Indiana, Kentucky, Michigan, Mississippi, Ohio and Tennessee due to the highly addictive nature and severe withdrawal symptoms. According to the U.S. Drug Enforcement Administration, tianeptine is abused for its euphoric properties similar to other opioids, such as heroin. Severe adverse health effects, including respiratory depression, severe sedation and death have occurred from misuse.

Tianeptine

The language in farm bill has been interpreted to mean that any hemp-derived product with less than 0.3% THC in its final form is legal. Make a 70-gram brownie out of hemp containing just under 0.3% THC, and you get 21 times more THC than you can get in California’s regulated cannabis market. 
Furthermore, with some chemistry, innovative hemp manufacturers can create an alphabet soup of chemically synthesized cannabinoids that can get you high, like delta-8 THC, THC-P, and THC-O. The Drug Enforcement Administration has pushed back and classified two such compounds as dangerous Schedule I substances. Still, the regulations on synthetic cannabinoids made from compounds that naturally occur in hemp remain overwhelmingly unenforced.    

Delta-8
conference, Delta-8

Support our efforts to end prohibition, fight for fairness, reduce crime, and boost local economies through marijuana policy reform.

  • Medical Marijuana
  • Legalization
  • Social Justice
policy

Pooling of data from the identified longitudinal studies showed that ever e-cigarette users have an increased likelihood for subsequent cannabis, alcohol, and unprescribed Ritalin/Adderall use compared to never e-cigarette users. The findings indicate a need for interventions to reduce e-cigarette use in adolescents and young adults.

Psychosis, Psychoactive, addiction

The bill that Robinson and Burton sponsored during the 2023 session originally would have limited the amount of THC (the main psychoactive compound in cannabis) in hemp products, but it faced a fierce pushback from members from the hemp industry as well as regular Floridians who say they rely on the product to deal with physical pain.
For example, in the House, the bill set THC limits not to exceed 5 milligrams per serving or 50 milligrams per package and prohibit those products to anyone under the age of 21. Ultimately, the bill sponsors removed the provision that would limit the THC amounts.
“We just ran out of time,” Robinson told the Phoenix on Wednesday. “We had to get it through the final committee hearing [and] we had 80 percent of the bill that everyone ...

Delta-8, Delta-8 FL
Delta-8 FL, Delta-8

TALLAHASSEE, Fla. — Today, Florida Commissioner of Agriculture Wilton Simpson announced the results of “Operation Kandy Krush,” the Florida Department of Agriculture and Consumer Services’ largest ever inspection sweep of food establishments selling products that contain hemp extracts. The week-long statewide inspection sweep targeted the illegal sale of hemp extract products that are attractive and/or marketed to children, prohibited by Florida Law. The sweep included inspections of more 475 food establishments in 37 Florida counties and uncovered 68,689 packages of hemp extract products — including euphoric, high-potency THC products — targeting children.

Delta-8, Delta-8 FL

July 3 (Reuters) - Wrigley, the maker of multi-colored fruit-flavored Skittles candies, has settled a lawsuit accusing a seller of cannabis-related merchandise of trademark infringement for marketing products under the "ZKITTLEZ" name.
Under a proposed permanent injunction filed on Monday in Chicago federal court, Terphogz LLC agreed not to use Skittles, Zkittlez or similar terms for cannabis-related sales.
Terphogz would stop using slogans such as "Taste the Z Train" and "Taste the Strain Bro," which Wrigley found too similar to Skittles' longtime slogan "Taste the Rainbow."
It also agreed to give up the domain name zkittlez.com, though it may use the letter "Z" if people will not be confused.

Delta-8, delta-8 lawsuit
Delta-8, powerpoint

Powerpoint presentation with excellent ideas to help motivate and engage your community to help educate everyone on any issue specifically drug prevention.

Delta-8, powerpoint

A mother in Spotsylvania County, Virginia, pleaded guilty Monday to involuntary manslaughter in the death of her 4-year-old son, who consumed a fatal amount of marijuana-infused gummies last year.
Authorities said Dorothy Annette Clements didn't get help soon enough for her son, Tanner Clements, when he was found unresponsive on May 6, 2022 at a home they were both visiting.
Tanner Clements died two days later. An autopsy found that THC caused the boy's death. THC is the active ingredient in marijuana that gets people high.

Delta-8, Delta-8 Children

In contrast, a liquid diamonds cart contains just cannabinoids and terpenes, so not only is the potency noticeably high [up to 92% THC], but incredibly smooth. Kater says, "As someone who's been consuming personally for 30 years, I vape a lot less these days [because] as I get older I cough a lot, my throat gets irritated. It's almost shocking when you take a big hit [of liquid diamonds] and you exhale, how smooth it is."

Medical marijuana, #FakeMedicine

The evidence presented in this review allows us to conclude that Δ9-THC and CBD produce biphasic, dose-dependent effects on several physiological responses. The biphasic nature of cannabinoid effects highlights the need for a careful analysis of the dose ranges separating therapeutic from unwanted effects. Besides, Δ9-THC produces dependence and harmful effects, while CBD does not.
The available pharmaceutical formulations of these phytocannabinoids and related molecules have clear therapeutic effects; however, more research is needed to assure their efficacy and safety since their effects are complex. Several additional potential therapeutic applications, mainly for CBD, are being proposed which, however, still lack sufficient clinical and preclinical support. For this reason, caution is advised when using or prescribing cannabinoids.
Additional consideration deserves the fact that the ECS participates in the development of the central nervous system98. Therefore, the use of cannabinoid-based formulations for the medical treatment of children and adolescents experiencing brain developmental changes must be carefully examined, balancing the pros and cons of prescribing cannabinoid-based medications in every single case. Cannabis research field is expanding with the identification of new molecular targets, the characterization of undescribed phytocannabinoids, and novel findings related to the ECS99. In addition, consumption of synthetic cannabinoids as drugs of abuse represents a new challenge in addiction research100.

Potency, study, Research, THC levels

U.S. Marshals, along with U.S. Food and Drug Administration (FDA) investigators, seized more than 250,000 units of dietary supplements and bulk dietary ingredients that are or contain kratom, including 1,000 kilograms of bulk kratom.

Mitragyna speciosa, or Kratom, is a plant that grows in certain Southeast Asian countries and has been indicated to have narcotic and stimulant-like effects.

The complaint alleges there isn’t enough information to provide assurance about the safety of kratom and consuming kratom can lead to serious health issues including respiratory depression, vomiting, nervousness, weight loss and constipation, the complaint states.

The compliant also says withdrawal symptoms may include hostility, aggression, excessive tearing, aching of muscles and jerky limb movements.

 

kratom

DeLoach said a 12-year-old female student reportedly was passing out and exhibiting symptoms of an overdose. The principal told deputies the child might have taken THC gummies along with three other students who may have eaten some as well.

Delta-8, Delta-8 FL

The bill originally envisioned a limit of 0.5 milligrams of THC per dose, or 2 milligrams per container, a proposal which rankled the hemp industry. The cap was subsequently lifted from 0.5 milligrams per serving to 5 milligrams per serving, and from 2 milligrams per package to 50 milligrams per package.
“All caps are O-U-T, out,” Robinson said.

Delta-8, Delta-8 FL

Dr. Roneet Lev- Years ago, she advocated against the overprescription of opioid painkillers like OxyContin. Now, she believes she’s seeing the same thing all over again: the specious claims of medical benefits, the denial of adverse effects. “From Big Tobacco to Big Pharma to Big Marijuana—it’s the same people, and the same pattern.”
Today, teenagers are “dabbing” a product that’s three, four, or five times stronger, (than 30 years ago) and are often doing so multiple times a day. At that level of potency, the impact of the drug on a user’s brain belongs to an entirely different category of risk than smoking a joint or taking a bong rip of even an intensively bred marijuana flower. It’s highly addictive, and over time, there’s a significant chance it can drive you insane.

Potency, Delta-8

In a committee meeting Monday, Manatee County House Republican Will Robinson Jr. said: “All caps are O.U.T., Out.”

Last month, the Village Board unanimously passed an ordinance that prohibits licensed tobacco and “smoke shop” operators from selling any products containing THC, the psychoactive ingredient in cannabis.  

delta-8 ban, Delta-8

I am an emergency and addiction physician who practices on the front lines of the emergency department. I had the honor to serve as the first Chief Medical Officer at the White House Office of National Drug Control Policy. Every shift I, along with my colleagues across the United States, treat patients with marijuana poisoning. CHS and Cannabis Induced Psychosis are the most common marijuana associated daily diagnosis in emergency departments across our country.

Delta-8, Delta-8 Children

"There is a gray area in state statue when it comes to these products. It's basically not being regulated," Johnson said at the Village Board meeting. "We are going to regulate it."

Delta-8, Ordinance

COOK COUNTY - Northwest suburban Elk Grove Village passed an ordinance Tuesday night that prohibits license tobacco stores from selling any products that contain THC — the ingredient in marijuana that makes users feel "high."
The ordinance was introduced after the village discovered a "gray area" in state law that allowed products containing THC that weren't FDA approved to be sold at smoke shops.

Some of the unregulated products were delta 8 vapes and edible candies such as gummy bears.

Delta-8, Ordinance

That provision reflects the state government’s position that consumer safety should override all other concerns in establishing laws to guide the hemp sector, sponsoring lawmakers said earlier.

A Virginia boy’s death last year was attributed to over-ingestion of delta-8 THC from eating gummies, leading to felony murder and felony child neglect charges against his mother. The death was officially ruled an accident attributable to “delta-8-tetrahydrocannabinol toxicity” by the Office of the Chief Medical Examiner Central District of Virginia, although some cannabis experts have cast doubt on that conclusion.

Delta-8, Death, Delta-8 Children

There are no FDA-approved drugs containing delta-8 THC. Any delta-8 THC product claiming to diagnose, cure, mitigate, treat, or prevent diseases is considered an unapproved new drug. The FDA has not evaluated whether these unapproved drug products are effective for the uses manufacturers claim, what an appropriate dose might be, how they could interact with FDA-approved drugs or other products, or whether they have dangerous side effects or other safety concerns. 
The warning letters address the illegal marketing of unapproved delta-8 THC products by companies as unapproved treatments for various medical conditions or for other therapeutic uses. The letters also cite violations related to drug misbranding (e.g., the products lack adequate directions for use) and the addition of delta-8 THC in foods, such as gummies, chocolate, caramels, chewing gum, and peanut brittle. 
“The FDA is very concerned about the growing popularity of delta-8 THC products being sold online and in stores nationwide. These products often include claims that they treat or alleviate the side effects related to a wide variety of diseases or medical disorders, such as cancer, multiple sclerosis, chronic pain, nausea and anxiety,” said FDA Principal Deputy Commissioner Janet Woodcock, M.D. “It is extremely troubling that some of the food products are packaged and labeled in ways that may appeal to children. We will continue to safeguard Americans’ health and safety by monitoring the marketplace and taking action when companies illegally sell products that pose a risk to public health.” 

The study, published May 4 by the Cambridge journal Psychological Medicine, examines 6.9 million people ages 16-49 and more than 45,000 schizophrenia cases from 1972 to 2021. It found that the adjusted incidence risk ratio for males ages 16 to 20 was more than twice that for females of the same age group, concluding that “[a]t a population level, assuming causality, one-fifth of cases of schizophrenia among young males might be prevented by averting CUD” (cannabis use disorder).

Cannabis-use disorder, mental health, Delta-8

A Californian sidewalk delta-8 vendor was recently arrested in Ocean Beach for selling unlicensed delta-8 products. The SDPD confiscated his inventory and cited him for possession of cannabis for sale. 

You cannot cross California state borders with delta-8 THC products unless they carry below 0.3% THC. The state restricts and regulates all unlicensed delta-8 products above the 0.3% combined THC concentration.
Likewise, you cannot enter California with marijuana-derived delta-8, even though the state legalizes medical and recreational cannabis. 
The federal government controls all state borders and considers marijuana illegal. Entering California with marijuana could be seen as drug trafficking, a felony crime. 

Delta-8

Key findings from the RDCOS March ‘23 issuance on novel and alternative cannabinoids include:

• There is significantly greater Delta-8 consumption in states where cannabis remains illegal than in states with adult-use cannabis markets.
• Past month consumption of Delta-8, Delta-8 THCO, Delta-10, THCP, THCV, CBN, and HHC each are associated with a greater prevalence of driving under the influence of cannabis (DUIC) and the severity of problematic cannabis use.
• Delta-8 consumption by past-year cannabis consumers has increased by 10% since December 2022.
• THCV, a cannabinoid commonly branded as “diet weed,” is the most popular alternative cannabinoid among past-year cannabis consumers.
• A total of 23% of 16–20-year-olds who consumed cannabis in the past year reported consuming Delta-8 at least monthly.

Delta-8

"I'm very concerned about seeing something called respiratory depression in children, where they're not breathing as well," she said. "Another thing that can be potentially deadly is they become so sleepy that they're not protecting their airway so they won't be able to breathe properly."

She said delta-8 can be 'incredibly dangerous' because it isn't regulated in Tennessee. 

"A gummy can say it's 50 milligrams, but it could be way more than that," she said. "It could be less, but the concerning thing is what if it's way more than that?" 

 

Delta-8, Delta-8 Children

The Georgia Supreme Court has cleared the way for Gwinnett County to resume raids, arrests and prosecutions to stop the sale of cannabis-derived products Delta-8 and Delta-10.
Cannabis-derived products containing very low THC amounts are broadly considered legal in Georgia and are widely available at shops around the state.
So when Gwinnett County cracked down on the products last year, shop owner Jennifer Byrd said her business was threatened and she took the county’s district attorney to court.

Delta-8

Pregnancy, Drug Free America

Article from pro-marijuana:
The issue is legislation in Florida that would limit how much THC such products are allowed to contain. Everyone, of course, is not going out of business, though Boyce’s company is at risk. The hemp industry will live on. Boyce’s note blamed the proposed legislation on “certain politicians” who are “heavily invested in the medical marijuana industry.”

This kind of thing is why licensed cannabis companies in legal states are increasingly disgusted by gray-market alt-THC peddlers. It’s not just the competition they face (after all, the hemp-derived products are aimed mostly at people in states where cannabis is still illegal). It’s also that fly-by-night operators tend to make the whole industry look bad, whether they’re selling iffy THC products or CBD gummies and oils that haven’t been tested and in some cases contain little or no CBD.

One relatively simple act could solve all these problems in one fell swoop: legalizing cannabis at the federal level.

Pro-pot, Delta-8
DEA, Delta-8, THC-O

If you're smoking a joint to enjoy the psychoactive effects of THC, then you might want to know how much of the potent cannabinoid is in a typical smoke. Here you'll learn how to calculate the amount of THC in a joint and understand what percentage of the cannabinoid your body is actually processing. 
The weight of the joint (in milligrams) multiplied by potency/THC percentage equals total milligrams of THC. 
One gram = 1000 milligrams. 
Example: The difference between a half gram and full gram joint of the same 20% THC flower:
1 gram: 1000 mg x 0.20 = 200 mg
Half gram: 500 mg x 0.20 = 100 mg
If you'd rather skip the math equations, a modern joint may contain between 60 to 150 mg of THC or more, representing a sharp increase from the approximately 10 mg common in the 1970s. 
The above formulas tell us how much THC is in a joint, but they tell us nothing about how much your body is absorbing from the joint. According to Rae, this number will depend on several factors that differ among individuals. These factors include:

  • Composition of the joint, i.e., ratio of THC to CBD
  • How much THC is wasted in sidestream smoke which wafts off at the end of a joint without being consumed, unlike mainstream smoke which is what you directly inhale and exhale
  • Smoking topography, aka your puff technique
  • Bioavailability (the proportion of THC that is able to activate the brain, after being introduced into the body and entering the bloodstream)

Rae elaborated on the key components of mainstream and sidestream smoke, saying, “The ratio of mainstream to sidestream smoke produced by a joint is highly variable because of differences in puff techniques. There are several factors in an individual puff. The volume of smoke per puff is typically about 35 milliliters but can be as big as 55 milliliters (for context, the volume of a shot glass is about 40 milliliters). This volume is determined by the force and amount of time a person inhales.”
Mainstream smoke is also affected by the frequency of inhalations, as Rae said, “Puffing more frequently increases the amount of THC consumed in mainstream smoke, and thus diminishes the amount of THC wasted in sidestream smoke.”
Ultimately, bioavailability is calculated by measuring the THC in the blood, and comparing that to how much THC you started with in the joint. Referencing research published in 2007 in the journal Chemistry & Biodiversity, Rae added, “Bioavailability is highly variable for inhalation: experiments in humans show that it ranges from 2% to 56% depending on the person.”
To illustrate bioavailability, Rae provided the following examples using one gram joints and half gram joints.

  • One gram joint = 200 mg THC. On the low end, 2%: 200 x 0.02 = 4 mg. On the high end, 56%: 200 x 0.56 = 112 mg.
    The bioavailable THC in a 1 gram joint with 20% THC is between 4  and 112 milligrams.
    Half gram joint = 100 mg THC. On the low end, 2%: 100 x 0.02 = 2 mg. On the high end, 56%: 100 x 0.56 = 56 mg.
    The bioavailable THC in a half-gram joint with 20% THC is between 2 and 56 milligrams
Potency

Introduction: Delta-8-tetrahydrocannabinol (THC) is a known isomer of delta-9-THC, both found naturally in the Cannabis sativa plant and thought to have similar potency. Delta-8-THC products are widely accessible in retail shops which may lead to a rise in pediatric exposures with substantial clinical effects.

Delta-8, Delta-8 Children

Conclusion: The first report of D8-THC, in the FAERS database, as a suspect drug appears to be in 2011. Overall, there are 183 total cases listing D8-THC as a suspect drug in the FAERS database as of June 30, 2021. Of the 183 cases, most were respiratory in nature.
 
FDA Adverse Event Reporting System (FAERS) Public Dashboard

Delta-8

Pregnancy
Delta-8

More than 5.4 million Americans are medical cannabis patients. In Florida alone, there are 788,297 medical cannabis cardholders as of Jan. 27 – a 1,107.01 percent increase since 2018.

BY GISELE GALOUSTIAN | 2/9/2023

 

In the United States, 49.6 million Americans ages 12 and older used cannabis or marijuana in 2020. More than 5.4 million Americans are medical cannabis patients. In Florida alone, where medical cannabis has been legal since 2014, there has been a 1,107.01 percent increase in the number of people with medical cannabis cards, from about 65,310 cardholders in 2018 to 788,297 as of Jan. 27.
One primary reason for the continued increase in cannabis use is risk perception. Many people believe cannabinoids – plant derived, medicinal, and synthetic or chemically engineered – are safe to use because they are non-psychotropic and non-psychoactive. However, for some people, cannabis can be addictive and potentially cause harm when taken with other substances such as alcohol or other drugs.
Despite its widespread use in the U.S. and globally (more than 200 million worldwide), little is known about deaths that are associated with or caused by using cannabinoids. 
Researchers from Florida Atlantic University’s Christine E. Lynn College of Nursing are the first to conduct a statewide analysis of deaths in Florida associated with cannabis and synthetic cannabis use, utilizing data from the Florida Department of Law Enforcement from 2014 to 2020. For the study, they examined sociodemographic characteristics, health-related conditions, the presence of other substances, and the type of death associated with the use of these substances.
Results, published in the Journal of Nursing Scholarship show that 386 people died as a result of cannabis use; of these, 258 cases were caused by synthetic cannabis. Nearly 65 percent of these cases involved synthetic cannabis as the only drug involved.
“Synthetic cannabinoids are part of the new psychoactive substances that are two to 100 times more potent than THC, the main psychoactive compound in marijuana,” said Armiel Suriaga, Ph.D., senior author and an assistant professor in FAU’s Christine E. Lynn College of Nursing. “Synthetic cannabinoids are manufactured chemicals sprayed onto dried, shredded leaves or plant materials that mimic the effect of cannabis, but their actual effects are unpredictable, harmful and deadly.”  
Findings showed that nearly 28 percent of deaths caused by cannabis and synthetic cannabis were in those ages 45 to 54, compared to 9 percent in those ages 8 to 24. This finding suggests a change in the age demographic in the context of mortality considering the attributable health conditions such as cardiovascular heart diseases.
More than 13 percent of cases had cardiac-related conditions such as hypertensive heart disease related to high blood pressure, atherosclerotic heart diseases, cardiac arrhythmias, and cardiomegaly, an enlarged heart. There was one case of death from an ischemic stroke and one case of a death from a hemorrhagic stroke, both related to synthetic cannabis use.
Among the study’s key findings:

  • Nearly 88 percent of those who died from cannabis and synthetic cannabis use were men.
  • Approximately 65 percent were non-Hispanic whites.
  • One hundred percent of cannabis-related deaths occurred in urban counties.
  • In rural counties, 28.3 percent of deaths were related to synthetic cannabis use; 39.9 percent were African American.

Nearly 99 percent of individuals using cannabis and synthetic cannabis died from accidents. Most of these accidents were due to drug intoxications (83.93 percent) and motor vehicular crashes or collisions (14.17 percent) that caused blunt traumas to the head and torso. More motor vehicular accidents were observed in cannabis use as a cause of death rather than synthetic cannabis use. Four individuals died from drowning under the influence of cannabis.
The highest count of deaths related to cannabis use was in 2019; the highest count for synthetic cannabis as a cause of death was in 2018. The lowest count of deaths from both substances ranged from one to three deaths, which occurred in 2014.
“The persistent deaths from cannabis and synthetic cannabis use are a legitimate public health concern,” said Suriaga. “The public should remain vigilant of the adverse health outcomes associated with these substances and their unpredictable effects, especially for men who are disproportionately affected, and particularly for people with underlying cardiovascular and respiratory conditions.”
Study co-authors are Ruth M. Tappen, Ed.D., RN, FAANthe Christine E. Lynn Eminent Scholar and professor, FAU Christine E. Lynn College of Nursing; and Elizabeth R. Aston, Ph.D., an assistant professor, Department of Behavioral and Social Sciences, Brown University School of Public Health.
This study was funded by the National Institute on Drug Abuse Substance Use Disorder Evidence- Based Practice Training Awards and the American Association of Colleges of Nursing.
-FAU-

Delta-8, synthetics, fatal, Death

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