Schizophrenia

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Title Tags Notes
Cannabinoid Shows Positive Results in Treating Schizophrenia Schizophrenia, gw pharm, CBD

Positive top-line results have been reported from an exploratory phase 2a placebo-controlled clinical trial of cannabidiol (CBD, GW Pharmaceuticals) in patients with schizophrenia who had failed to respond adequately to first-line antipsychotic medications.  DOES NOT CONTAIN THC.

Cannabis use may influence cortical maturation in adolescent males Schizophrenia, males

Male teens who experiment with cannabis before age 16, and have a high genetic risk for schizophrenia, show a different brain development trajectory than low risk peers who use cannabis.

How Cannabis Causes Paranoia: Using the Intravenous Administration of Δ9-Tetrahydrocannabinol (THC) to Identify Key Cognitive Mechanisms Leading to Paranoia Schizophrenia, paranoia, Studies, Research

The principal psychoactive constituent of cannabis is Δ9-tetrahydrocannabinol (THC). THC administered intravenously is characterized by the appearance of psychopharmocological effects within 5 minutes, which continue for at least 90 minutes, providing an excellent experimental window.[12] In within-subjects tests with nonclinical volunteers, D'Souza, in particular, has shown that intravenous administration of THC causes schizophrenia-like symptoms, perceptual disturbances, anxiety, and impaired working memory (eg, Morrison et al[13] and D'Souza et al[14,15]). Similar but more pronounced results were found in patients with schizophrenia.[15]

Teen cannabis users have poor long-term memory in adulthood youth, memory, Schizophrenia

The study is among the first to say the hippocampus is shaped differently in heavy marijuana smokers and the different looking shape is directly related to poor long-term memory performance.
The study also found that young adults with schizophrenia who abused cannabis as teens performed about 26 percent more poorly on memory tests than young adults with schizophrenia who never abused cannabis.

tudy finds genetic links between schizophrenia and cannabis use Schizophrenia
Cannabis Use during Adolescent Development: Susceptibility to Psychiatric Illness adolescent, Psychiatric, addiction, Schizophrenia, opioid, Studies
Teens who smoke pot at risk for later schizophrenia, psychosis Teens, Schizophrenia

Evidence is mounting that regular marijuana use increases the chance that a teenager will develop psychosis, a pattern of unusual thoughts or perceptions, such as believing the television is transmitting secret messages. It also increases the risk of developing schizophrenia, a disabling brain disorder that not only causes psychosis, but also problems concentrating and loss of emotional expression.

Documentary Links Marijuana Use with Psychosis, Schizophrenia Psychosis, Schizophrenia
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