risks

But  the  lives  of  vulnerable  people  may  be  put  at  risk when  science  is  distorted  for corporate  or  ideological  ends.  As  noted,  several  USstates  responded  to the  much-hypedoriginal study of cannabis and opioid overdosesby authorizing the use of medical cannabis to treat  heroin-addicted  individuals.  Advice  that  opioid  users  should use medical  cannabis toreplace  opioid  agonist  therapies  (e.g.,  methadone,  buprenorphine) poses significant  risk because abrupt cessation of these medications dramatically increases the risks of an overdose death if users return to opioid use 

"We've seen children that have had rather severe reactions while on medical marijuana products," said Amy Brooks-Kayal, M.D., a Colorado pediatrician who is president of the American Epilepsy Society. "We don't know if that's from the medical marijuana product or something else, because it wasn't done in a controlled setting."
Dr. Brooks-Kayal supports the clinical trials underway now across the country, and advises parents not to treat their sick children with cannabis oil until clinicial trials are complete.
"Just because a single child or person or even a few may respond well to a treatment, that doesn't mean that the majority of them will," she said.