Placebo

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Medical Marijuana for Pain: What the Evidence Shows meta-analysis, Studies, Placebo, pain

Twenty-eight studies were undertaken to evaluate the effectiveness of cannabinoids for chronic pain. Of these, only 2 were found to be at low risk of bias. 

Overall, these studies seem to indicate that cannabinoids have a significant role to play in the management of chronic pain. However, there are important issues that limit the validity of this conclusion. First and most important is how the improvement in pain was evaluated. In many of the studies, only instruments to measure the level of pain, most notably the Visual Analogue Scale, were used. This is fine when one is measuring acute pain. But when it comes to chronic pain—which is what the studies were looking at—the most important measures of the impact of any treatment are improvement in functioning and other objective measures, such as reduction in use of analgesic medications. 

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Placebo Effect: A Cure in the Mind Placebo

Mr. Wright was confident that a new anticancer drug called Krebiozen would cure him. Mr. Wright’s tumors had shrunk by half, and after 10 more days of treatment he was discharged from the hospital. And yet the other patients in the hospital who had received Krebiozen showed no improvement.

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American Cancer Society- What is the placebo effect? American Cancer Society, Placebo

Even though they don’t act on the disease, placebos affect how some people feel. This happens in up to 1 of 3 people. A change in a person’s symptoms as a result of getting a placebo is called the placebo effect. Usually the term “placebo effect” speaks to the helpful effects a placebo has in relieving symptoms. This effect usually lasts only a short time. It’s thought to have something to do with the body’s natural chemical ability to briefly relieve pain and certain other symptoms.

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Putting the placebo effect to work Harvard, Placebo 4
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