CANNABIS: DRUG OF ABUSE AND THERAPEUTIC AGENT, TWO SIDES OF THE SAME COIN
05/27/2023 |
The evidence presented in this review allows us to conclude that Δ9-THC and CBD produce biphasic, dose-dependent effects on several physiological responses. The biphasic nature of cannabinoid effects highlights the need for a careful analysis of the dose ranges separating therapeutic from unwanted effects. Besides, Δ9-THC produces dependence and harmful effects, while CBD does not.
The available pharmaceutical formulations of these phytocannabinoids and related molecules have clear therapeutic effects; however, more research is needed to assure their efficacy and safety since their effects are complex. Several additional potential therapeutic applications, mainly for CBD, are being proposed which, however, still lack sufficient clinical and preclinical support. For this reason, caution is advised when using or prescribing cannabinoids.
Additional consideration deserves the fact that the ECS participates in the development of the central nervous system98. Therefore, the use of cannabinoid-based formulations for the medical treatment of children and adolescents experiencing brain developmental changes must be carefully examined, balancing the pros and cons of prescribing cannabinoid-based medications in every single case. Cannabis research field is expanding with the identification of new molecular targets, the characterization of undescribed phytocannabinoids, and novel findings related to the ECS99. In addition, consumption of synthetic cannabinoids as drugs of abuse represents a new challenge in addiction research100.
Potency, study, Research, THC levels |
Todays Marijuana is not just a plant
01/15/2023 |
THC is the mind-altering ingredient in marijuana that affects behavior and alters perception, mood or consciousness. The public deserves to be informed about the wide variety of products and THC potencies sold in marijuana markets.
THC levels |
Not Your Mom’s Pot: How Increased Potency Has Changed Marijuana Consumption
08/05/2016 |
Marijuana is typically four-times stronger than it was a couple decades ago. On top of the boosted potency, since legalization, growers have been able to refine their skills to grow strains for unique and specific ailments. Not to mention the exploding market of concentrates and dab culture.
Potency, THC, THC levels |
THC extracts concentrate problems
06/07/2015 |
The proliferation of foods infused or coated with THC has become a growing concern, even among some marijuana advocates. Several high-profile marijuana crimes and deaths involve consumption of edible THC products.
“When THC is available in food, it’s even harder for people to see it as a drug,” Lewis said. “But it is a drug. It is a depressant, a hallucinogen and an addictive substance that changes chemistry in the brain. Research shows all of the above.”
clearing the haze, Potency, THC levels |
Ed Wood- FL per se law
02/01/2015 |
Based upon the foregoing evidence, this author has a clear preference for zero tolerance laws to deal with the increasing scourge of DUID. The increasingly accepted Libertarian view is that such laws criminalize personal choices that cause no harm to citizens other than the drug consumer. Laws requiring probable cause be first established before requiring a blood sample theoretically alleviate this concern, but are unconvincing to opponents of zero-tolerance laws. Adoption of New Zealand’s approach is suggested as a means of gaining acceptance of zero tolerance laws without unduly harming Libertarian sensitivities.
Wood, Potency, 2017 Legislation, THC levels, THC |
Futile Search
02/01/2015 |
The fact is that there is no level of THC in blood above which everyone is impaired, and below which no one is impaired. This is not because we need more studies; it’s because of human biology. Consider the following three factors.
Wood, Potency, 2017 Legislation, THC levels, THC |
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