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Marijuana use is associated with an increased risk of prescription opioid use.  
Marijuana use seems to strengthen the relationship between pain and depression and anxiety, not ease it.

"Every person I've ever asked that has a drug addiction problem, I would ask them intentionally 'what was your drug of choice that set you on this path?' Marijuana. Every time, marijuana," Judd said.
He went on to say that when you look at all the drugs killing people and contributing to drug related deaths, "leaving marijuana out of the recipe would be a horrible mistake."

“The violence is there with other drugs, but we don’t see the homicides associated with other narcotics as we do with marijuana,” said Anoka County Sheriff’s Lt. Wayne Heath, commander of the Anoka-Hennepin Narcotics and Violent Crimes Task Force. “No one knows why in marijuana it leads to that extra step.”

An 11-month-old Colorado boy’s death from a heart condition was likely related to ingestion of marijuana, two Denver doctors have concluded, but the precise link remains unclear.

Cryptococcal meningitis in a daily cannabis smoker without evidence of immunodeficiency.
Cryptococcal meningitis is a life-threatening condition most commonly observed in immunocompromised individuals. We describe a daily cannabis smoker without evidence of immunodeficiency presenting with confirmed Cryptococcus neoformans meningitis. An investigation of cannabis samples from the patient's preferred dispensary demonstrated contamination with several varieties... Read More

New research reveals that several species, including the northern spotted owl, are succumbing to rat poison from thousands of "unpermitted private marijuana grow sites" in the northwestern California counties of Humboldt, Mendocino and Del Norte.
It's the contamination of the owls' primary food source — mice and rats, which, like humans, are attracted to the aromatic crop — that has been the animals' undoing... Read More

Tetra Health Care, a California-based chain that hires licensed doctors to write medical marijuana recommendations at six clinics in Florida, is closing all but one to focus on working with state lawmakers to make access easier for patients, a spokeswoman said.

UC San Diego — along with every other University of California System institution, all of the California State University System, community colleges and private colleges — does not allow marijuana on university grounds or in campus buildings.

But she didn't have cancer. She had an obscure syndrome called cannabinoid hyperemesis syndrome, a condition only recently acknowledged by the medical community. It affects a small population — namely, a subset of marijuana users who smoke multiple times a day for months, years or even decades.

There's no hard data on the prevalence of the illness. But in California and Colorado, which have loosened marijuana laws in recent years, some emergency physicians say they're... Read More

bstract

Although recent Cannabis use is widely reported to be associated with drug-related traffic accidents, the evidence that Cannabis users show an increased risk of being involved in road crashes is still not unequivocally proved. The purpose of the present work is to provide an objective assessment of this hypothesis, by comparing the frequency of occurrence of positive urine analyses in drivers involved in traffic accidents (n = 1406) with that observed in a control population... Read More

Law enforcement officials applauded Sessions' move.

"We applaud the Attorney General for this action today that brings clarity on enforcement of the law by rescinding a confusing policy brought on by the previous administration that hindered law enforcement. This will allow sheriffs to carry out their mission of upholding the rule of law and keeping their communities safe," said National Sheriffs' Association President Harold Eavenson and Executive Director Jonathan... Read More

WASHINGTON - The Department of Justice today issued a memo on federal marijuana enforcement policy announcing a return to the rule of law and the rescission of previous guidance documents. Since the passage of the Controlled Substances Act (CSA) in 1970, Congress has generally prohibited the cultivation, distribution, and possession of marijuana.
In the memorandum, Attorney General Jeff Sessions directs all U.S. Attorneys to enforce the laws enacted by Congress and to follow well-... Read More

Conclusions:

Cannabis use appears to increase rather than decrease the risk of developing nonmedical prescription opioid use and opioid use disorder.

Community-by-community, residents of Massachusetts are deciding if they want to be able to drive to the corner store to buy marijuana.

NIH’s 2017 Monitoring the Future survey shows both vaping and marijuana are more popular than traditional cigarettes or pain reliever misuse

there is incomplete evidence of the efficacy and safety of medical use of cannabis in the clinical contexts considered in this review. Furthermore, for many of the outcomes considered, the confidence in the estimate of the effect was again low or very low. To give conclusive answers to the efficacy and safety of cannabis used for medical purposes in the clinical contexts considered, further studies are needed, with higher quality, larger sample sizes, and possibly using the same diagnostic... Read More

He is no longer employed by Amtrak. No amount of marijuana use by an engineer is acceptable, the railroad has said.

“My job is to represent the people of Jacksonville Beach and as I mentioned during the council meeting, 81 percent of the people may have voted for medical marijuana. But it wasn’t 81 percent of Jacksonville Beach residents looking to put a dispensary in Jacksonville Beach,” Mayor Charlie Latham said.
#NotInMyBackyard

The overlapping endocannabinoid and endogenous opioid systems may explain this patient's response to therapy, and this synergistic relationship is discussed.
The endocannabinoid and endogenous opioid systems are syngergistic, which may explain the effect of naloxone in cannabis toxicity. Cannabinoid and opioid receptors belong to the rhodopsin subfamily of G-protein-coupled receptors which, when activated, reduce cellular levels of cyclic adenosine monophosphate (cAMP) by inhibiting... Read More

The number of drivers involved in fatal crashes in Colorado who tested positive for marijuana has risen sharply each year since 2013, more than doubling in that time, federal and state data show. A Denver Post analysis of the data and coroner reports provides the most comprehensive look yet into whether roads in the state have become more dangerous since the drug’s legalization.

Council members cite lack of local control as reason. The city of Venice will ban medical marijuana dispensaries within city limits, because current state statutes do not allow any form of local regulation above those placed on pharmacies. 
In moving toward prohibiting dispensaries, Venice joins the city of Sarasota and town of Longboat Key, though Sarasota is looking to modify its approach that would treat dispensaries the same as stand-alone pharmacies.

“The best long-term solution is prevention,” Sessions said. “The best action is not to start. Just say no.”

Those three words — embraced by First Lady Nancy Reagan in the 1980s to discourage young people from using recreational drugs — are back.

On Friday, as Summit County released its latest overdose numbers for the past seven days — 58 residents sought help in... Read More

Kentucky's ban on medical marijuana has survived an initial test in court, with a judge ruling Wednesday that the state has a good reason to "curtail citizens' possession of a narcotic, hallucinogenic drug."

Kentucky's ban on medical marijuana has survived an initial test in court, with a judge ruling Wednesday that the state has a good reason to "curtail citizens' possession of a narcotic, hallucinogenic drug."

We therefore must educate our youngsters, parents and educators before any use of marijuana or alcohol begins. We then must identify those individuals for whom marijuana or alcohol use has become problematic, getting them into an effective program of treatment before they progress to more dangerous alternatives.
 
Schools must revamp curriculums so children understand that any opioid misuse, be it prescription or street drugs, is a "red line" that they cannot cross.

Updated information on Florida counties and city councils banning 'medical' marijuana dispensaries.

Snelling argued that not everyone using medical marijuana is severely ill, with symptoms like insomnia, mood swings and chronic itching qualifying for the drug. She said she is worried misuse will be widespread.
“Voting for something to be legalized as a medicine by popular vote or through legislative does not make it a prescription drug,” said Miller.

Two local mothers showed up at the pow-wow to voice their concerns about an influx of dispensaries. One of the mothers, Teresa Miller, believes cannabis acts as a gateway drug.
“Years ago, when my son smoked pot and spring boarded to opioids, a severe addiction, I told myself if I could save one family from going through what our family and thousands of families around our state have gone through with a disease of addiction, then I would,” Miller said.
Miller also showed the... Read More

Indian River County joined many governments across the state banning dispensaries rather than accepting them as pharmacies, the only other option allowed in a state law adopted this summer.

Marijuana’s Negative Effects
Construction workers must have full use of their skills and faculties while performing their jobs. Medical marijuana may have positive medical benefits, but there are also well-documented negative effects. Some negative effects to the central nervous system include changes in sensory perception, altered thought formation and expression, short-term memory problems, and impaired thinking and learning. Negative physical effects include... Read More

The largest increases in opioid-related deaths in Florida from 2014 to 2015 were from the following drugs: Buprenorphine (up 102 percent), heroin (up 74 percent), fentanyl (up 69 percent), codeine (up 57 percent), and Oxymorphone (up 42 percent).

“The facts of the accident included Mr. Siegler being the driver of a vehicle while under the influence of marijuana,” the Sheriff’s Office said in a press release. “He subsequently crossed the center lane of travel striking another oncoming vehicle.
Siegler was arrested at his home in rural Rochester and booked into the Thurston County Jail.
Siegler referenced the crash and apparent remorse in a June 30 post on his Facebook page, saying he wanted to pay his respects and that “... Read More

"We found no observational studies that met inclusion criteria, but a growing body of cross-sectional literature suggests negative opioid-related correlates among individuals who use cannabis and opioids concurrently. These include opioid misuse;... Read More

Abstract

Contemporary models of substance use disorders emphasize the role of cognitive control, which has been linked to difficulties in resisting the use of substances. In the present study, we measured two aspects of cognitive control, response inhibition (operationalized by a Go/NoGo Task) and performance monitoring (operationalized by an Eriksen Flanker Task), in a group of young cannabis-use disorder (CUD) patients and compared these functions with two control groups (i.e. a... Read More

Drug users now cause almost as many traffic deaths in Michigan as drunken drivers, a trend police blame on prescription drugs, the opioid epidemic and the easy availability of marijuana, medical and otherwise.
Over the past decade, fatal drunken-driving crashes across the state are down 36%, while those caused by people impaired by drugs have risen 263%.

They say they took their daughter to counseling, rehab summer camps, anything to help with her marijuana use and mental health struggles. The day before her overdose, she had passed two drug tests.  Her parents thought they had finally turned a corner.

Reports have shown a staggering increase in cannabis-related emergency department (ED) visits in recent years. In 2011, the Substance Abuse and Mental Health Services Administration (SAMHSA) and Drug Abuse Warning Network (DAWN) estimated a total of 1.25 million illicit-drug–related ED visits across the US, of which 455,668 were marijuana related.2 A similar report published in 2015 by the Washington Poison Center Toxic Trends Report showed a dramatic increase in cannabis-related ED visits.3... Read More

“Duration of marijuana use seems to be a significant factor associated with metabolic syndrome,” the researchers said.
Metabolic syndrome is a cluster of symptoms that increase a person’s risk for heart disease, stroke and diabetes.
The study found that “every year increase in marijuana use is associated with at least a 5 percent increase in odds of having metabolic syndrome.”

“His consistent use of marijuana affected his brain structure,” Gomez-Mallada said.  But Cox ruled: “The court finds there is little possibility of rehabilitation. The defendant is a danger.” Marshall’s accomplice, Henry, has pleaded guilty to second-degree murder and is scheduled for sentencing in July.

After retail marijuana sales began in Colorado, the increase in collision claim frequency was 14 percent higher than in nearby Nebraska, Utah and Wyoming. Washington's estimated increase in claim frequency was 6.2 percent higher than in Montana and Idaho, and Oregon's estimated increase in claim frequency was 4.5 percent higher than in Idaho, Montana and Nevada.

“John is an old friend who shares the same values [of] trying to hold government accountable and make it more efficient,” Corcoran said. “We share that mission.”
Morgan had been the driving force behind the referendum approved by voters last year, and a bill outlining how medical marijuana regulations would work was passed Friday during the Legislature’s special session. 

“The pill mills were everywhere,” said Teresa Miller. We had our van stolen from our front yard one Saturday night, and it was abandoned in Brooksville with drugs in it. I don’t want this to happen again, and I don’t want that type of clientele walking through our neighborhood again.”

First, dosing of smoked marijuana remains unpredictable. And although much of the medical marijuana debate centers on the effects of single exposures, insufficient information exists regarding the effects of repeated exposures. Approximately 10% of people routinely using marijuana become addicted, with a higher incidence amongst adolescents. Tolerance and down-regulation of receptors have been documented with repeated marijuana use. A marijuana withdrawal syndrome has also been recognized,... Read More

Aside from the changes to criminal law, legalization has implications for school safety policies, child abuse and neglect statutes, child care center regulation, advertising restrictions, substance abuse programs, employment law, traffic offenses, banking, state revenue, ports of entry and federalism, among many others.
These policy challenges have far-reaching implications, few have been easy to resolve, and most have drawn time and resources away from other policy areas. But most... Read More

Authorities said a toddler nearly died from eating edible marijuana. The Rhode Island Department of Children, Youth and Families on Friday announced the 2-year-old girl had almost died Thursday and had been admitted to the pediatric intensive care unit at Hasbro Children’s Hospital.

But he was also the teen who began smoking marijuana at 14 before turning to oxycontin two years later. He wrecked his mother's car while driving stoned, pilfered money from his friends, dropped out of high school and spent three weeks in jail after his parents turned him in for stealing their credit cards.

The town suddenly became a haven for recreational pot users, drawing in transients, panhandlers and a large number of homeless drug addicts, according to officials and business owners. Many are coming from New Mexico, Arizona and even New York.
He said he’s also noticed an uptick in crime in the area. Shoplifting, he said, has become a major problem in Durango and business owners are becoming fed up.