Article Date | Link | Tags | Body |
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06/01/2020 | Association Between the Use of Cannabis and Physical Violence in Youths: A Meta-Analytical Investigation | meta-analysis, Research |
After screening 11,348 potential studies....These results demonstrate a moderate association between cannabis use and physical violence, which remained significant regardless of study design and adjustment for confounding factors (i.e., socioeconomic factors, other substance use). Cannabis use in this population is a risk factor for violence. |
05/08/2020 | Cannabis Increases Propensity for False Memories | Research, memory, false memories |
To look for longer-term effects of cannabis, the experimenters called the subjects back a week later and tested them again on the word lists, this time with a few different dummy words thrown in. They also re-interviewed the subjects about the VR scenarios using a combination of old and new questions. As before, they found lower memory accuracy in the word-association test in those who had been intoxicated compared with sober participants. There were no statistically significant differences between the groups for the virtual reality scenarios, a result that Kloft says may indicate memory decay over time in all participants. |
09/08/2019 | Reducing the risks of distortion in cannabis research | Research, Medical, risks, opioid |
But the lives of vulnerable people may be put at risk when science is distorted for corporate or ideological ends. As noted, several USstates responded to the much-hypedoriginal study of cannabis and opioid overdosesby authorizing the use of medical cannabis to treat heroin-addicted individuals. Advice that opioid users should use medical cannabis toreplace opioid agonist therapies (e.g., methadone, buprenorphine) poses significant risk because abrupt cessation of these medications dramatically increases the risks of an overdose death if users return to opioid use |
08/12/2019 | Association Between Electronic Cigarette Use and Marijuana Use Among Adolescents and Young Adults | meta-analysis |
Conclusions and Relevance This meta-analysis found a significant increase in the odds of past or current and subsequent marijuana use in adolescents and young adults who used e-cigarettes. These findings highlight the importance of addressing the rapid increases in e-cigarette use among youths as a means to help limit marijuana use in this population. |
03/19/2019 | cannabis use to variation in the incidence of psychotic disorder across Europe | Research, study, Lancet, Potency, Psychosis |
In conclusion, our findings confirm previous evidence of the harmful effect on mental health of daily use of cannabis, especially of high-potency types. Importantly, they indicate for the first time how cannabis use affects the incidence of psychotic disorder. Therefore, it is of public health importance to acknowledge alongside the potential medicinal properties of some cannabis constituents the potential adverse effects that are associated with daily cannabis use, especially of high-potency varieties. |
07/01/2018 | Cannabis use and driving-related performance in young recreational users: a within-subject randomized clinical trial | Canada, Research, study, driving, youth |
We found that among young recreational cannabis users, a regular dose of cannabis had no effect on simple and learned tasks, but its use led to significant impairments on complex and novel driving-related tasks, as well as perceived driving ability and safety, for up to 5 hours after use. The present finding that the first 5 hours after cannabis use affected driving-related performance substantiates the recommendations of Canada’s Lower-Risk Cannabis Use Guidelines, which recommend waiting 6 hours after cannabis use before driving.30 |
04/17/2018 | Medical Marijuana Users are More Likely to Use Prescription Drugs Medically and Nonmedically | opioid, study, Research |
Conclusions: Our findings disconfirm the hypothesis that a population-level negative correlation between medical marijuana use and prescription drug harms occurs because medical marijuana users are less likely to use prescription drugs, either medically or nonmedically. Medical marijuana users should be a target population in efforts to combat nonmedical prescription drug use. |
04/14/2018 | Mood Fluctuation and Psychobiological Instability: The Same Core Functions Are Disrupted by Novel Psychoactive Substances and Es | Research, Psychoactive |
Many novel psychoactive substances (NPS) have entered the recreational drug scene in recent years, yet the problems they cause are similar to those found with established drugs. This article will debate the psychobiological effects of these newer and more traditional substances. It will show how they disrupt the same core psychobiological functions, so damaging well-being in similar ways. |
04/08/2018 | Review of the public health risks of widespread cannabis use | Pregnancy, car crashes, mental health, pediatrics, Long-term, Doctors, Research, second hand smoke, smoking |
1. Legalizing cannabis has been shown to increase the rates of motor vehicle accidents. |
01/08/2018 | "Positive" urine testing for Cannabis is associated with increased risk of traffic crashes | Research, car crashes, drug testing |
bstract Although recent Cannabis use is widely reported to be associated with drug-related traffic accidents, the evidence that Cannabis users show an increased risk of being involved in road crashes is still not unequivocally proved. The purpose of the present work is to provide an objective assessment of this hypothesis, by comparing the frequency of occurrence of positive urine analyses in drivers involved in traffic accidents (n = 1406) with that observed in a control population undergoing mandatory urine drug testing (n = 1953). Urine analyses for drugs of abuse were performed by screening immunometric techniques followed by confirmation with UHPLC-QQQ MS, adopting a cut-off concentration for THC-COOH of 15 ng/mL. A case was classified as "positive" when a driver admitted to hospital for road traffic injuries showed urine concentrations of THC-COOH higher than the cut-off. All samples showing positive results for any other controlled drug in urine or blood alcohol concentrations >0.5 mg/mL were excluded from the study. Subjects positive to THC-COOH, and negative to all the other tested substances were 116 in Group 1 (8.2%) and 16 in Group 2 (0.8%). Subjects resulting negative to any tested substances were 1290 in Group 1 and 1937 in Group 2. The frequency of THC-COOH detection in the two groups was compared by using the "chi square" test, which resulted = 119.57, i.e. highly significant (P <<< 0.01). The Odds Ratio of the two groups was =10.88, showing a high degree of association between the presence of THC-COOH in urine and the occurrence of traffic accidents (P < 0.0001). The presented data, proving a high degree of association between Cannabis use and the occurrence of traffic accidents with injuries of the driver, support the use of urine testing for Cannabis in the procedures for the issuing of the driving licence, particularly in the case of subjects formerly or presently using Cannabis. This finding looks even more relevant in the present times, because of the increasing success of the policies of legalization of Cannabis for medical and non-medical purposes.
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04/20/2017 | ‘Medical’ marijuana is incompatible with mental health promotion | Research, mental health |
Similarly, it can be anticipated that if introduced, the indications for the use of medical cannabinoids would expand well outside of the initial indications. Hence, the medical profession cannot justify the use of medical cannabinoids that would be associated with an iatrogenic risk of serious adverse psychological events. The use of medical cannabinoids for any purpose, including research under closely observed conditions, is incompatible with mental health promotion. |
03/18/2017 | Marijuana use and physical dating violence among adolescents and emerging adults: A systematic review and meta-analysis. | meta-analysis, PDV, adolescent, Studies, Research, ncbi |
Findings suggest that marijuana use is associated with a 54% increase in the odds PDV (physical dating violence) victimization, and a 45% increase in the odds of perpetration. CONCLUSIONS: Findings suggest that dating violence is a correlate of marijuana use, and that association is strongest among adolescents (vs. emerging adults) and girls (vs. boys). |
03/18/2017 | Long lasting effects of chronic heavy cannabis abuse. | ncbi, chronic, impaired, delusions, Long-term, Studies, Research |
The existence of hallucinations, delusions, and organic brain dysfunction in heavy cannabis users seems to be associated with cannabinoid levels in hair. The continuation of persistent symptoms 3 months after the discontinuation of cannabis abuse, was a remarkable finding. SCIENTIFIC SIGNIFICANCE: We provide evidence that chronic and heavy cannabis abuse results in long-lasting brain dysfunction in all users and in long-lasting schizophrenia-like psychotic symptoms in more than half of all users. These findings suggest a reevaluation of the current classification of cannabis as a "soft narcotic" which erroneously, therefore, is typically considered harmless. (Am J Addict 2017;XX:1-8). |
02/14/2017 | Marijuana Is Not Safe to Smoke, Researchers Say | smoking, Research, second hand smoke |
The mold and bacteria was so widespread and potentially dangerous that the UC Davis academics concluded that they cannot recommend smoking raw or dried weed. "We cannot recommend inhaling it," says George Thompson III, an associate professor of clinical medicine at the university who helped conduct the cannabis research. |
02/13/2017 | Is the Hype of Medical Marijuana All Smoke and Mirrors? | MM Regulations, Studies |
Short-term side effects include impaired short-term memory, impaired motor function, altered judgment, and, in high doses, paranoia and psychosis. Not to mention that drivers who have recently smoked marijuana are twice as likely to get into a car accident than their sober counterparts.Approximately 9% of people who experiment with marijuana will become addicted. |
02/08/2017 | GW Pharma Reports Success with THC and CBD Combo in Brain Cancer Phase 2 Clinical Trial | gw pharm, Studies, cancer | |
01/17/2017 | Marijuana Violence and Law | Research, Journal of Addiction, crime, violence, mental health, withdrawal symptoms |
According to research studies, marijuana use causes aggressive behavior, causes or exacerbates psychosis and produce paranoias. These effects have been illustrated through case studies of highly publicized incidents and heightened political profiles. Marijuana is currently a growing risk to the public in the United States. Following expanding public opinion that marijuana provides little risk to health, state and federal legislatures have begun changing laws that will significantly increase accessibility of marijuana. Greater marijuana accessibility, resulting in more use, will lead to increased health risks in all demographic categories across the country. Violence is a well-publicized, prominent risk from the more potent, current marijuana available. |
01/06/2017 | Heavy Marijuana Use May Alter Dopamine System Much Like Heroin and Cocaine | Studies, dopamine, Skywood |
“But the bottom line is that long-term, heavy cannabis use may impair the dopaminergic system, which could have a variety of negative effects on learning and behavior,” said Dr. Anissa Abi-Dargham, professor of psychiatry and a lead author of the paper. |
01/06/2017 | The Clinical Conundrum of Medical Marijuana | Potency, Studies, driving, Finn, MD, 2017 Legislation |
Detailed Information
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11/14/2016 | Marijuana use may be linked to temporarily weakened heart muscle | heart, Studies, Research, American Heart Association |
"This development of stress cardiomyopathy in younger patients who used marijuana suggests a possible link that needs to be further investigated," said Sahil Agrawal, M.D., co-author of the paper and also a chief cardiology fellow at St. Luke's. Marijuana users were more likely than non-users to have a history of depression (32.9 percent vs. 14.5 percent), psychosis (11.9 percent vs. 3.8 percent), anxiety disorder (28.4 percent vs. 16.2 percent), alcoholism (13.3 percent vs. 2.8 percent), tobacco use (73.3 percent vs. 28.6 percent) and multiple substance abuse (11.4 percent vs. 0.3 percent). Because some of these can increase the risk of stress cardiomyopathy, the researchers adjusted for known risk factors to investigate the association between marijuana use and stress cardiomyopathy. |
11/01/2016 | Educational Outcomes | education, PubMed, Studies |
CONCLUSIONS: |
10/19/2016 | Δ9-THC Intoxication by Cannabidiol-Enriched Cannabis Extract in Two Children with Refractory Epilepsy: Full Remission after Swit | Charlotte's Web, Studies, CBD |
The children presented typical signs of intoxication by Δ9-THC (inappropriate laughter, ataxia, reduced attention, and eye redness) after using a CBD-enriched extract. The extract was replaced by the same dose of purified CBD with no Δ9-THC in both cases, which led to improvement in intoxication signs and seizure remission. |
09/01/2016 | Complexities in understanding and addressing the serious public health issues related to the nonmedical use of prescription drug | Studies, Research, Prescription, epidemic, 2017 Legislation |
A common theme among every article in this issue is the overlap be- tween NMUPD, excessive drinking, and marijuana and other forms of substance use. In every investigation, nonmedical users were observed to have a history of using alcohol, marijuana, tobacco, and other psycho- active substances. Kalyanam, Katsuki, Lanckriet, and Mackey (2017) |
08/31/2016 | What Scientific & Medical Journals & Experts Say About Marijuana | Arizona, Research |
30 Referenced Resources |
08/20/2016 | PubMed | PubMed, Studies | |
06/26/2016 | Yale Study Shows Danger of Marijuana | Veterans, PTSD, Studies |
“In this observational study,” it found that “initiating marijuana use after treatment was associated with worse PTSD symptoms, more violent behavior, and alcohol use. Marijuana may actually worsen PTSD symptoms or nullify the benefits of specialized, intensive treatment. Cessation or prevention of use may be an important goal of treatment.” |
05/08/2016 | Study shows marijuana users twice as likely to give birth prematurely | Pregnancy, Studies |
For the researchers of the study, the results present a “a major public health concern” as a number of pregnant women would report taking marijuana to alleviate morning sickness or nausea – without knowing of the adverse side-effects. http://www.sciencedirect.com/science/article/pii/S0890623816300715# Highlights
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04/01/2016 | Marijuana Use: Detrimental to Youth | American Academy of Pediatrics, youth, Research, Side-Effects |
In summary, marijuana use is harmful to children and adolescents. For this reason, the American College of Pediatricians opposes its legalization for recreational use and urges extreme caution in legalizing it for medicinal use. Likewise, the American Academy of Child and Adolescent Psychiatry (AACAP) recently offered their own policy statement opposing efforts to legalize marijuana. They similarly pointed out that “marijuana’s deleterious effects on adolescent brain development, cognition, and social functioning may have immediate and long-term implications, including increased risk of motor vehicle accidents, sexual victimization, academic failure, lasting decline in intelligence measures, psychopathology, addiction, and psychosocial and occupational impairment.” Thus the AACAP (a) opposes efforts to legalize marijuana, (b) supports initiatives to increase awareness of marijuana’s harmful effects on adolescents, (c) supports improved access to evidence-based treatment, rather than emphasis on criminal charges, for adolescents with cannabis use disorder, and (d) supports careful monitoring of the effects of marijuana-related policy changes on child and adolescent mental health.49 The College agrees with this position on marijuana. |
03/20/2016 | Marijuana Use Increases Violent Behavior | violence, Studies, crime |
What makes this new study more compelling than previous studies is that the researchers followed the same individuals for over 50 years from a young age to adulthood. This is precisely what one needs to solve the chicken or egg riddle with respect to cannabis and violence: just look and see which one happens first. |
03/10/2016 | Substance Abuse and Mental Illness: Effects of Marijuana and Other Drugs on Developing Psychosis | Psychosis, Studies |
• Rates of cannabis use are approximately 2 times greater in persons with psychosis |
02/20/2016 | Study Links Marijuana Use to Greater Risk for Developing Addiction to Other Drugs | addiction, youth, Studies |
A new study suggests marijuana smokers may be significantly more likely to develop an addiction to other drugs and alcohol than people who don’t use marijuana. |
01/09/2016 | Persistent Cannabis Dependence and Alcohol Dependence Represent Risks for Midlife Economic and Social Problems: A Longitudinal C | alcohol, addiction, Studies |
Our data indicate that persistent cannabis users constitute a burden on families, communities, and national social-welfare systems. Moreover, heavy cannabis use and dependence was not associated with fewer harmful economic and social problems than was alcohol dependence. Our study underscores the need for prevention and early treatment of individuals dependent on cannabis. |
01/04/2016 | Adolescent Cannabinoid Exposure Induces a Persistent Sub-Cortical Hyper-Dopaminergic State and Associated Molecular Adaptations | Brain, adolescent, Research |
Thus, adolescent THC exposure induced behavioral abnormalities resembling positive and negative schizophrenia-related endophenotypes and a state of neuronal hyperactivity in the mesocorticolimbic dopamine (DA) pathway. Furthermore, we observed profound alterations in several prefrontal cortical molecular pathways consistent with sub-cortical DAergic dysregulation. Our findings demonstrate a profound dissociation in relative risk profiles for adolescent versus adulthood exposure to THC in terms of neuronal, behavioral, and molecular markers resembling neuropsychiatric pathology. |
12/29/2015 | Pot Science: Top Marijuana Findings of 2015 | Research, usage, college, Resource Paper, edibles, Teens |
Although studies are beginning to show that some ingredients in marijuana are likely to be helpful for people with certain conditions, the findings have yet to nail down the specifics about the dose, the frequency, the best form to take (such as getting the active compounds from edible products or smoking it), the risks from frequent use, and whether marijuana works as well as or better than other available treatments, Budney said. |
12/09/2015 | EFFICACY AND SAFETY OF EPIDIOLEX (CANNABIDIOL) IN CHILDREN AND YOUNG ADULTS WITH TREATMENT-RESISTANT EPILEPSY: UPDATE FROM THE E | Charlotte's Web, american epiliepsy society, AES, Studies |
These results from an uncontrolled study support the animal studies and prior reports showing that CBD may be a promising treatment for TRE and it is generally well-tolerated in doses up to 25mg/kg/day. Epidiolex is now being investigated in randomized controlled studies in DS and LGS. |
11/28/2015 | Study: High-potency marijuana linked with neural damage | Studies, Brain, Potency |
"We found that frequent use of high-potency cannabis significantly affects the structure of white matter fibres in the brain, whether you have psychosis or not," |
11/05/2015 | UF researchers granted $1 million for epilepsy study | Epidiolex, Orphan Study, Florida |
The project is intended to treat 50 children from ages 2 to 16 living with epilepsy that have exhausted most of their treatment options, Carney said. |
11/03/2015 | More Positive Results With Cannabidiol in Epilepsy | Epidiolex, Studies, Orphan Study, gw pharm |
More Positive Results With Cannabidiol in Epilepsy (You will need to google this title in order to get the article to avoid creating an account) |
10/11/2015 | Medical Assoications Response | response, medical association, Research |
The American Medical Association (AMA) has opposed legalizing marijuana for medical use for many years due to the lack of evidence to support such action. In addition to AMA, the following medical associations also oppose legalizing marijuana or any of its components for medical use before FDA-quality evidence is available. |
10/11/2015 | Cannabis, cannabinoids and cancer – the evidence so far | cancer, hash oil, Research |
At the moment, there simply isn’t enough evidence to prove that cannabinoids – whether natural or synthetic – works to treat cancer in patients, although research is ongoing. And there’s certainly no evidence that ‘street’ cannabis can treat cancer. |