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Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis

Summary: Significant psychiatric risks associated with high-THC cannabis concentrates, demonstrating that even in healthy adults, THC can induce a range of psychiatric symptoms, including psychosis. Given these findings, there's a strong argument for legislative action to limit THC potency in marijuana products to a maximum of 15% to safeguard public health. This precautionary measure is particularly crucial as the legal status of cannabis may lead individuals to perceive it as safe. Legislators have a responsibility to protect the public by implementing regulations that address the potency of cannabis products, prioritizing the well-being of those who may not be aware of the risks associated with high-THC consumption.

Potency, Psychosis
he prospective association between the use of E-cigarettes and other psychoactive substances in young people

Pooling of data from the identified longitudinal studies showed that ever e-cigarette users have an increased likelihood for subsequent cannabis, alcohol, and unprescribed Ritalin/Adderall use compared to never e-cigarette users. The findings indicate a need for interventions to reduce e-cigarette use in adolescents and young adults.

Psychosis, Psychoactive, addiction
Risk of depressive disorders associated with medical cannabis authorization: A propensity score matched cohort study

Our study showed that patients with medical cannabis authorization have a higher risk of emergency department visits or hospitalizations for depression compared to patients with no authorization. Our results also suggest that this risk is increased among patients without prior mental health disorders at cannabis authorization. The findings emphasize the need for a careful risk-benefit assessment that takes into account this observation prior to cannabis authorization. Further longitudinal

Medical, Psychosis, science direct
Johnnys Ambassadors- Mental Illness and Marijuana

Articles on link between mental illness and marijuana

Johnnys Ambassadors, mental health, cannabis-induced psychosis, Psychosis, youth
Association of Cannabis Use-Related Predictor Variables and Self-Reported Psychotic Disorders: U.S. Adults, 2001-2002 and 2012-2013

Data from the U.S. general population, especially more recent data, suggest associations between self-reported psychotic disorder and frequent nonmedical cannabis use and cannabis use disorder. Clinicians and policy makers should consider these relationships when monitoring patients and formulating programs.   (Nonmedical use does not mean they didn't use medical marijuana but used to get high or selfmedicated.)

cannabis-induced psychosis, NIH, Psychosis
Cannabis and Psychosis: Recent Epidemiological Findings Continuing the “Causality Debate”

In summary, much of the available evidence supports the criteria of strength, consistency, biological gradient, and temporality for cannabis causing psychosis. Furthermore, supporting specificity, while many substances are known to induce psychosis, the risk for conversion to schizophrenia is greatest with cannabis-induced psychosis.

cannabis-induced psychosis, Research, Psychosis
cannabis use to variation in the incidence of psychotic disorder across Europe

In conclusion, our findings confirm previous evidence of the harmful effect on mental health of daily use of cannabis, especially of high-potency types. Importantly, they indicate for the first time how cannabis use affects the incidence of psychotic disorder. Therefore, it is of public health importance to acknowledge alongside the potential medicinal properties of some cannabis constituents the potential adverse effects that are associated with daily cannabis use, especially of high-potency varieties.

Research, study, Lancet, Potency, Psychosis, cannabis-induced psychosis
Daily Marijuana Use And Highly Potent Weed Linked To Psychosis

The study authors consider high-potency cannabis to be products with more than 10 percent tetrahydrocannabinol or THC, the compound responsible for the drug's psychoactive effects. The fact that consuming high-THC cannabis products has a greater risk is concerning, Lisdahl says, because these products are more common in the market now.

Now a new study published Tuesday in the The Lancet Psychiatry shows that consuming pot on a daily basis and especially using high-potency cannabis increases the odds of having a psychotic episode later.

study, Potency, Lancet, Psychosis
Association between cannabis use and psychosis-related outcomes using sibling pair analysis in a cohort of young adults.

Early cannabis use is associated with psychosis-related outcomes in young adults. The use of sibling pairs reduces the likelihood that unmeasured confounding explains these findings. This study provides further support for the hypothesis that early cannabis use is a risk-modifying factor for psychosis-related outcomes in young adults.

Truth, hallucinations, cannabis-induced psychosis, Psychosis
Effects of Marijuana on Mental Health


2. Marijuana classification... CESAR

mental health, depression, anxiety, impaired, Psychosis, suicide, Drug Free America
Cannabis-Induced Psychosis: A Review

Reports have shown a staggering increase in cannabis-related emergency department (ED) visits in recent years. In 2011, the Substance Abuse and Mental Health Services Administration (SAMHSA) and Drug Abuse Warning Network (DAWN) estimated a total of 1.25 million illicit-drug–related ED visits across the US, of which 455,668 were marijuana related.2 A similar report published in 2015 by the Washington Poison Center Toxic Trends Report showed a dramatic increase in cannabis-related ED visits.3 In states with recent legalization of recreational cannabis, similar trends were seen.

cannabis-induced psychosis, Psychosis
Association Between Continued Cannabis Use and Risk of Relapse in First-Episode Psychosis

Using a quasi-experimental design wherein we assessed cannabis use patterns after the onset of psychosis, we were able to investigate the causal nature of the association between cannabis use and risk of relapse in psychosis. Although it has been proposed that a common genetic liability or reverse causation may underlie the association between continued cannabis use and relapse,13 our results indicate that change in cannabis use represents a robust risk factor for relapse in patients with FEP.

Marijuana use in adolescence may increase risk for psychotic symptoms

Analysis indicated that for each year adolescent boys engaged in regular marijuana use, their projected level of subsequent subclinical psychotic symptoms increased by 21% and projected risk for subclinical paranoia or hallucinations increased by 133% and 92%, respectively.

youth, adolescent, Psychosis
Pot-related psychosis linked to early ‘dangerous’ use

“They told me I was having a psychotic episode brought on by cannabis,” said Thibodeau, who requested that the Star use his grandmother’s surname as he is still recovering from the breakdown.
“I was shocked. We live in a society where there is such a culture around smoking dope that people think it is cool to be a stoner. Nobody ever talks about the pitfalls.”

Substance Abuse and Mental Illness: Effects of Marijuana and Other Drugs on Developing Psychosis

• Rates of cannabis use are approximately 2 times greater in persons with psychosis
• Cannabis has negative effects on cognition that are qualitatively similar in the general population, in people with psychotic disorders and in people at risk for psychotic disorders
• Adolescence is an important but vulnerable period of development for both the general population and especially for individuals at high risk for psychotic disorders

Psychosis, Studies
Potent Pot: Marijuana Is Stronger Now Than It Was 20 Years Ago

Pot is becoming more potent, a new study suggests.
In the study, the researchers looked at more than 38,600 samples of illegal marijuana seized by the U.S. Drug Enforcement Administration over 20 years. They found that the level of THC, or tetrahydrocannabinol— marijuana's main psychoactive ingredient — in the marijuana samples rose from about 4 percent in 1995 to about 12 percent in 2014.
Conversely, the level of CBD, or cannabidiol — an ingredient sometimes touted for its potential health benefits — fell from about 0.28 percent in 2001 to less than 0.15 percent in 2014.
But smoking marijuana with high doses of THC may involve a higher risk of negative health effects, such as psychosis orpanic attacks, he said.
"Great article- clearly based on the previous posted comments  marijuana severely impairs a person's ability to understand and process information. Their anecdotal evidence continues to validate scientific statistics. " -No2Pot

CBD, Psychosis, Potency
Marijuana Triggers Psychotic Symptoms In Male Users

Trends in cannabis use suggest that twice as many males as females use the drug. This gender ratio is mirrored in rates of psychosis with males outnumbering females by 2:1. However, researchers at the University of York found there is a significant widening of this ratio for cannabis psychosis, where males outnumber females by four to one.


males, Psychosis
Teen Marijuana Use And The Risks Of Psychosis

The number of patients admitted with psychotic episodes after having consumed cannabis has more than tripled in Germany over the last 15 years, from 3,392 in 2000 to 11,708 in 2013. More than half of the patients are younger than 25.


Psychosis, Germany
Proportion of patients in south London with first-episode psychosis attributable to use of high potency cannabis: a case-control study
Studies, Psychosis, London
Cannabis and psychosis: Neurobiology

Cannabis is involved in approximately 50% of psychosis, schizophrenia, and schizophreniform psychosis cases Cannabis is a known risk factor for schizophrenia, although the exact neurobiological process through which the effects on psychosis occur is not well understood. Cannabis is also of particular interest in both the first-episode psychosis (FEP) and the ultra high risk (UHR) populations. This is mainly due to their increased susceptibility to cannabis abuse.

cannabis-induced psychosis, ncbi, Psychosis
Legalization, Decriminalization & Medicinal Use of Cannabis:A Scientific and Public Health Perspective
Research, Studies, Psychosis, Glaucoma, mental health, organs, risks
Marijuana Use Precedes the Onset Of Psychotic Symptoms In Youth and Young Adults
Teens, Psychosis
Documentary Links Marijuana Use with Psychosis, Schizophrenia
Psychosis, Schizophrenia
“Pot Is More Dangerous than LSD or Heroine” - Liberal UK Newspaper Apologizes for Efforts to Legalize
Danger, Psychosis, Studies
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