Pharmacokinetics

Current sort has key articles at the top. Click on "Article Date" to sort by date, click on specific "tag" to view all articles in that category.

Title Tags Notes
Marijuana or Alcohol: Which is more harmful? alcohol, harm, Potency, Pharmacokinetics, powerpoint

PowerPoint Presentation comparing Marijuana & Alcohol,

Cannabinoid Pharmacokinetics Cannabinoid, Pharmacokinetics

Pharmacokinetics encompasses the absorption of cannabinoids following diverse routes of administration and from different drug formulations, the distribution of analytes throughout the body, the metabolism of cannabinoids by different tissues and organs, the elimination of cannabinoids from the body in the feces, urine, sweaty oral fluid, and hair, and how these processes change over time. Cannabinoid pharmacokinetic research has been especially challenging because of low analyte concentrations, rapid and extensive metabolism, and physio-chemicaI characteristics that hinder the separation of drugs of interest from biological matrices and from each other, and that lower drug recovery because of adsorption of compounds of interest to multiple surfaces. Mass spectrometric developments now permit highly sensitive and specific measurement of cannabinoids in a wide variety of biological matrices.

Cannabinoid Pharmacokinetics Pharmacokinetics, Cannabinoid
Cannabis / Marijuana ( Δ 9 -Tetrahydrocannabinol, THC) NHTSA, THC, Pharmacokinetics, driving

Decreased car handling performance, increased reaction times, impaired time and distance estimation, inability to maintain headway, lateral travel, subjective sleepiness, motor incoordination, and impaired sustained vigilance have all been reported. Some drivers may actually be able to improve performance for brief periods by overcompensating for self-perceived impairment. The greater the demands placed on the driver, however, the more critical the likely impairment. Marijuana may particularly impair monotonous and prolonged driving. Decision times to evaluate situations and determine appropriate responses increase. Mixing alcohol and marijuana may dramatically produce effects greater than either drug on its own.

Subscribe to Pharmacokinetics